Compile Data Set for Download or QSAR
Found 203 with Last Name = 'garrido' and Initial = 'a'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM50609298(CHEMBL5268404)copy SMILES
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM50609298(CHEMBL5268404)copy SMILES
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProstacyclin receptor(RAT)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-iloprost from recombinant rat IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-iloprost from recombinant human IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]-iloprost from recombinant human IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-iloprost from recombinant human IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50272695(3-(4-chloro-2-morpholinothiazol-5-yl)-2,6-dimethyl...)copy SMILEScopy InChI
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAmyloid-beta precursor protein(Homo sapiens (Human))TBA
LigandPNGBDBM50122787(2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...)copy SMILEScopy InChI
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProstacyclin receptor(RAT)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Displacement of [3H]-iloprost from recombinant rat IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstacyclin receptor(RAT)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  76nMAssay Description:Displacement of [3H]-iloprost from recombinant rat IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation count...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235380(CHEMBL3917503)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Displacement of [3H]-iloprost from recombinant human IP receptor expressed in CHO-K1 cell membranes incubated for 1 hr by top count scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  570nMAssay Description:Displacement of [3H]-PGE2 from recombinant human EP2 receptor expressed in HEK293 cell membranes incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  678nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235370(CHEMBL3933704)copy SMILEScopy InChI
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]-PGD2 from recombinant human DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-PGD2 from recombinant human DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235385(APD-811 | Ralinepag)copy SMILEScopy InChI
Affinity DataKi:  9.60E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-BRL 43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50272695(3-(4-chloro-2-morpholinothiazol-5-yl)-2,6-dimethyl...)copy SMILEScopy InChI
Affinity DataKi:  1.69E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)copy SMILES
Affinity DataIC50: 0.0900nMMore data for this Ligand-Target Pair
In DepthDetails
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)copy SMILES
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609288(CHEMBL5268087)copy SMILES
Affinity DataIC50: 0.310nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM285634(3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...)copy SMILEScopy InChI
Affinity DataIC50: 0.488nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))TBA
LigandPNGBDBM50609297(CHEMBL5285673)copy SMILES
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProteinase-activated receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50609292(CHEMBL5273903)copy SMILES
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM350389(4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyri...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM285634(3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))TBA
LigandPNGBDBM50609297(CHEMBL5285673)copy SMILES
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50609287(CHEMBL5284720)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM285634(3-(4-chloro-3,5-difluoro-phenyl)-N-cyclopropyl-imi...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM610450(2-Phenyl-N-(pyridin-3-yl)imidazo[1,2-b]pyridazine-...)copy SMILES
Affinity DataIC50: 5.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))TBA
LigandPNGBDBM50364776(CHEMBL1952141 | CHEMBL1952329)copy SMILEScopy InChI
In DepthDetails
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23954(5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))TBA
LigandPNGBDBM610463(BDBM610464 | BDBM610465 | N-(4-(2-Methylmorpholino...)copy SMILES
Affinity DataIC50: 9.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCalcium-dependent protein kinase 1(Plasmodium Falciparum)TBA
LigandPNGBDBM50609296(CHEMBL5282946)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProstacyclin receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235375(CHEMBL3975122)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Agonist activity at IP receptor in human primary platelets assessed as inhibition of ADP-induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0JSMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))TBA
LigandPNGBDBM11835(1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-a]py...)copy SMILEScopy InChI
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50609295(CHEMBL5269179)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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