Compile Data Set for Download or QSAR
Found 41 with Last Name = 'golonko' and Initial = 'a'
TargetProteasome subunit beta type-5(Rattus norvegicus)
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50535250(CHEMBL471604)copy SMILEScopy InChI
Affinity DataIC50: 71.3nMAssay Description:Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50135169((-)-Catechin gallate | (2S,3R)-2-(3,4-dihydroxyphe...)copy SMILEScopy InChI
Affinity DataIC50: 124nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Rattus norvegicus)
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50380997(BROUSSONIN B)copy SMILEScopy InChI
Affinity DataIC50: 178nMAssay Description:Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50236531((-)-gallocatechin gallate | (2R,3S)-5,7-dihydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 187nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50153015((-)-Epicatechin-3-gallate | (-)-epicatechin 3-O-ga...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Rattus norvegicus)
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50535252(CHEMBL4457323)copy SMILEScopy InChI
Affinity DataIC50: 234nMAssay Description:Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of caspase-like activity of human 26S proteasome assessed as decrease in fluorescence using Z-Nle-Pro-Nle-Asp-aminoluciferin as substrate ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Rattus norvegicus)
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50535251(CHEMBL1078369)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of chymotrypsin-like activity of rat liver 26 proteasome assessed as decrease in fluorescence using succinyl-Leu-Leu-Val-Tyr-4-methylcouma...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome extracted from human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as substrate in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50042944((E)-1-(2,4-Dihydroxy-phenyl)-3-(4-hydroxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50535254((2S)-7-Hydroxyflavanone | CHEBI:41888 | CHEMBL4027...)copy SMILEScopy InChI
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | 5,7-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human HCT-116 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human SW480 cells assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50325671((2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIH...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50325671((2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIH...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Arg-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of trypsin-like activity of human 26S proteasome assessed as decrease in AMC hydrolysis using Ac-Arg-Leu-Arg-AMC as substrate incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.16E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.88E+4nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human 26S proteasome extracted from human LNCap cells assessed as decrease in AMC hydrolysis using Suc-Le...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50535253((-)-Medicarpin | CHEBI:100 | CHEMBL238845)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50021398(CHEBI:18088 | FORMONONETIN | NSC-93360)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50241408((2S)-liquiritigenin | 7-HYDROXY-2-(4-HYDROXY-PHENY...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of chymotrypsin-like activity of purified human erythrocyte 20S proteasome assessed as decrease in AMC hydrolysis using Suc-LLVY-AMC as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50187665((-)-epigallocatechin | CHEMBL47386)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute of Agricultural and Food Biotechnology

Curated by ChEMBL
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+6nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7TB3PubMed