Compile Data Set for Download or QSAR
Found 161 with Last Name = 'hamze' and Initial = 'a'
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50564716(CHEMBL4790926)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50564717(CHEMBL4787876)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DGXPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)copy SMILEScopy InChI
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KJ3PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50564718(CHEMBL4781618)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50564719(CHEMBL4793858)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432281(CHEMBL2347671)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50564720(CHEMBL4788045)copy SMILES
Affinity DataIC50: 59nMAssay Description:Inhibition of human GSK3beta in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432287(CHEMBL2347677)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50506580(CHEMBL4517272)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DGXPubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))TBA
LigandPNGBDBM50564720(CHEMBL4788045)copy SMILES
Affinity DataIC50: 64nMAssay Description:Inhibition of human CDK9/cyclin T in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50564720(CHEMBL4788045)copy SMILES
Affinity DataIC50: 70nMAssay Description:Inhibition of human GSK3alpha by ADP-Glo assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432286(CHEMBL2347667)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5Q4MPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432280(CHEMBL2347672)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432285(CHEMBL2347668)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432279(CHEMBL2347673)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50564716(CHEMBL4790926)copy SMILES
Affinity DataIC50: 117nMAssay Description:Inhibition of human GSK3beta in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))TBA
LigandPNGBDBM50564716(CHEMBL4790926)copy SMILES
Affinity DataIC50: 121nMAssay Description:Inhibition of human CDK5/p25 in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50592728(CHEMBL5183440)copy SMILES
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KJ3PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432287(CHEMBL2347677)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50564718(CHEMBL4781618)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of human GSK3beta in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50564716(CHEMBL4790926)copy SMILES
Affinity DataIC50: 162nMAssay Description:Inhibition of human CDK2/cyclin A in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432281(CHEMBL2347671)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))TBA
LigandPNGBDBM50564717(CHEMBL4787876)copy SMILES
Affinity DataIC50: 195nMAssay Description:Inhibition of human CDK5/p25 in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432286(CHEMBL2347667)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50564719(CHEMBL4793858)copy SMILES
Affinity DataIC50: 216nMAssay Description:Inhibition of human GSK3beta in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432278(CHEMBL2347674)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50506582(CHEMBL4448903)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DGXPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432280(CHEMBL2347672)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 272nMAssay Description:Inhibition of human CDK5/p25 in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMedDrugBank
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432284(CHEMBL2347669)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50592729(CHEMBL5199279)copy SMILES
Affinity DataIC50: 280nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KJ3PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432283(CHEMBL2346675)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))TBA
LigandPNGBDBM50564718(CHEMBL4781618)copy SMILES
Affinity DataIC50: 284nMAssay Description:Inhibition of human CDK5/p25 in presence of ATP by ADP-glo luminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P649ZPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432277(CHEMBL2347675)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432282(CHEMBL2347670)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432285(CHEMBL2347668)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432276(CHEMBL2347676)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432284(CHEMBL2347669)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1TFSPubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50506578(CHEMBL4542119)copy SMILEScopy InChI
Affinity DataIC50: 340nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KJ3PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Universit£ Paris-Saclay

Curated by ChEMBL
LigandPNGBDBM50506578(CHEMBL4542119)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins using fluorogenic substrate by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DGXPubMed
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