Compile Data Set for Download or QSAR
Found 504 with Last Name = 'hobbs' and Initial = 'a'
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118668(CHEMBL3617086)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118669(CHEMBL3617083)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118637(CHEMBL3617084)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118672(CHEMBL3617082)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530304(CHEMBL4445989)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530304(CHEMBL4445989)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118524(CHEMBL3617080)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118588(CHEMBL3617095)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118523(CHEMBL3617079)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530295(CHEMBL4453927)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118610(CHEMBL3617102)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530295(CHEMBL4453927)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118607(CHEMBL3617098)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530292(CHEMBL4444514)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530292(CHEMBL4444514)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118637(CHEMBL3617084)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118522(CHEMBL3617078)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118669(CHEMBL3617083)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118521(CHEMBL3617077)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118668(CHEMBL3617086)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118524(CHEMBL3617080)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATc (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118672(CHEMBL3617082)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118578(CHEMBL3617094)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530294(CHEMBL4538292)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118589(CHEMBL3617096)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530294(CHEMBL4538292)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530310(CHEMBL4545184)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530310(CHEMBL4545184)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530265(CHEMBL4559739)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530290(CHEMBL4529307)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530265(CHEMBL4559739)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118609(CHEMBL3617100)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530309(CHEMBL4456576)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530291(CHEMBL4448349)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530291(CHEMBL4448349)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530309(CHEMBL4456576)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530290(CHEMBL4529307)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530292(CHEMBL4444514)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530294(CHEMBL4538292)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530264(CHEMBL4466568)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118520(CHEMBL3617075)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118523(CHEMBL3617079)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530294(CHEMBL4538292)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530264(CHEMBL4466568)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530269(CHEMBL4538256)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530292(CHEMBL4444514)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Displacement of Myr-GQQPGKVLGDQRRPSL(K-TAMRA)G-amide from N-terminal-truncated human c-ABL D382N mutant (46 to 534 residues) after 30 mins by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50530269(CHEMBL4538256)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Activation of full length human 6His-tagged c-Abl expressed in baculovirus expression system using abltide as substrate after 2 hrs by IMAP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X92FR3PubMed
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