Compile Data Set for Download or QSAR
Found 36 with Last Name = 'hoffmann' and Initial = 'a'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F9DPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50037255((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F9DPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50037257((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F9DPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50037254((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F9DPubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst AG

Curated by ChEMBL
LigandPNGBDBM50037256((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F9DPubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465104(CHEMBL4284791)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465104(CHEMBL4284791)copy SMILEScopy InChI
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+7nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)copy SMILEScopy InChI
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)copy SMILEScopy InChI
Affinity DataKd:  1.80E+6nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataKd:  2.17E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)copy SMILEScopy InChI
Affinity DataKd:  510nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataKd:  2.10E+5nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)copy SMILEScopy InChI
Affinity DataKd:  8.80E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465106(CHEMBL3392935)copy SMILEScopy InChI
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465107(CHEMBL4292664)copy SMILEScopy InChI
Affinity DataKd:  3.43E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465105(CHEMBL1235691)copy SMILEScopy InChI
Affinity DataKd:  320nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465104(CHEMBL4284791)copy SMILEScopy InChI
Affinity DataKd:  4.59E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465105(CHEMBL1235691)copy SMILEScopy InChI
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to Influenza A virus M2 transmembrane domain by analytical ultracentrifugation methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765JBVPubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataKd:  130nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50465106(CHEMBL3392935)copy SMILEScopy InChI
Affinity DataKd:  340nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50465105(CHEMBL1235691)copy SMILEScopy InChI
Affinity DataKd:  320nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)copy SMILEScopy InChI
Affinity DataKd:  510nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataKd:  4.44E+5nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)copy SMILEScopy InChI
Affinity DataKd:  130nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465106(CHEMBL3392935)copy SMILEScopy InChI
Affinity DataKd:  340nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataKd:  2.17E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ71F3PubMed