Compile Data Set for Download or QSAR
Found 52 with Last Name = 'illendula' and Initial = 'a'
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123672(US8748618, AI-4-49)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123674(US8748618, AI-4-48)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123675(US8748618, AI-10-3)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123684(US8748618, LD-2-101)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123665(US8748618, AI-10-47)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123673(US8748618, LD-2-23)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123670(US8748618, LD-1-39)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123671(US8748618, AI-10-51)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123659(US8748618, AI-4-70 (or) LD-2-21)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123669(US8748618, AI-4-43)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123657(US8748618, LD-1-29 (or) AI-10-54)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434071(US10562890, Compound Al-12-16)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434079(US10562890, Compound Al-14-72)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123663(US8748618, AI-10-35)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180737(5,6-dimethyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123685(US8748618, AI-10-77)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123678(US8748618, AI-10-96)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434076(US10562890, Compound Al-14-100)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180732(5-Chloro-2-pyridin-2-yl-1H-benzoimidazole | 5-chlo...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123681(US8748618, AI-10-87)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123680(US8748618, AI-10-11)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123679(US8748618, AI-4-61 (or) AI-10-52)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123668(US8748618, LD-1-33)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180735(5-fluoro-2-(pyridin-2-yl)-1H-benzo[d]imidazole | 5...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123661(US8748618, AI-10-61)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434070(US10562890, Compound Al-10-104)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434075(US10562890, Compound Al-14-95)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50180733(5-Methyl-2-pyridin-2-yl-1H-benzoimidazole | 5-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434074(US10562890, Compound Al-14-91)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123682(US8748618, AI-10-53)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434069(US10562890, Compound Al-10-47)copy SMILEScopy InChI
Affinity DataIC50: 3.19E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123664(US8748618, AI-10-37)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123676(US8748618, AI-10-88)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123658(US8748618, AI-4-42)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123667(US8748618, LD-1-23)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123662(US8748618, LD-1-138)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434072(US10562890, Compound Al-14-55)copy SMILEScopy InChI
Affinity DataIC50: 4.83E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434078(US10562890, Compound Al-14-18)copy SMILEScopy InChI
Affinity DataIC50: 4.97E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123666(US8748618, AI-4-46)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123656(US10562890, Compound 4a | US8748618, AI-4-52)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434073(US10562890, Compound Al-12-126)copy SMILEScopy InChI
Affinity DataIC50: 8.91E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123654(US8748618, AI-4-57 (or) LD-1-11C | US8748618, LD-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetCore-binding factor subunit beta(Homo sapiens (Human))
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM123683(US8748618, AI-10-65)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:We have developed effective assays to monitor the inhibition of CBFβ-SMMHC binding to the Runt domain (as well as for CBFβ binding to the R...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25M64C7US Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM123656(US10562890, Compound 4a | US8748618, AI-4-52)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434066(US10562890, Compound 3b)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434065(US10562890, Compound Al-4-57)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434067(US10562890, Compound 3c)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
UNIVERSITY OF VIRGINIA PATENT FOUNDATION

US Patent
LigandPNGBDBM434065(US10562890, Compound Al-4-57)copy SMILEScopy InChI
Affinity DataIC50: 3.43E+4nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
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