Compile Data Set for Download or QSAR
Found 26 with Last Name = 'jouanen' and Initial = 'a'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022550(4-Hydroxy-2-(1-hydroxy-propyl)-8-trifluoromethyl-q...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50367740(CHEMBL1907766)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022555(4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carb...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357460(CHEMBL1917729)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022550(4-Hydroxy-2-(1-hydroxy-propyl)-8-trifluoromethyl-q...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357458(CHEMBL1917727)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357459(CHEMBL1917728)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50367739(CHEMBL1907769)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022556(2-Dichloromethyl-4-hydroxy-8-trifluoromethyl-quino...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50367740(CHEMBL1907766)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022556(2-Dichloromethyl-4-hydroxy-8-trifluoromethyl-quino...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022553(CHEMBL36075 | Propionic acid 1-[4-hydroxy-3-(thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022554(4-Hydroxy-8-trifluoromethyl-quinoline-3-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022553(CHEMBL36075 | Propionic acid 1-[4-hydroxy-3-(thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022555(4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carb...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357461(CHEMBL1917723)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50367739(CHEMBL1907769)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM50022554(4-Hydroxy-8-trifluoromethyl-quinoline-3-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357457(CHEMBL1917726)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357455(CHEMBL1917724)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357456(CHEMBL1917725)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HSP90beta in human SKBR3 cells assessed as down regulation of HER2 expression levels after 24 hrs by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of bovine Prostaglandin G/H synthase after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre de Recherches Roussel Uclaf

Curated by ChEMBL
LigandPNGBDBM85245(CAS_36322-90-4 | NSC_4856 | Piroxicam)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JM2B7TPubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM50357454(CHEMBL1917878)copy SMILEScopy InChI
Affinity DataKd:  0.350nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Sanofi-Aventis Research and Development

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)copy SMILEScopy InChI
Affinity DataKd:  7.30nMAssay Description:Binding affinity to human Hsp90beta after overnight incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4XH4PubMed