Compile Data Set for Download or QSAR
Found 37 with Last Name = 'kanter' and Initial = 'a'
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130312(4-[12-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylm...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nMAssay Description:Inhibitory constant of the compound for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130313(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)copy SMILEScopy InChI
Affinity DataKi:  0.0330nMAssay Description:Inhibitory constant of the compound for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataKi:  0.0420nMAssay Description:Inhibitory constant of the compound for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibitory constant of the compound for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataKi:  0.810nMAssay Description:Inhibitory constant of the compound for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)copy SMILEScopy InChI
Affinity DataKi:  25.9nMAssay Description:Inhibitory constant of the compound for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130312(4-[12-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylm...)copy SMILEScopy InChI
Affinity DataKi:  212nMAssay Description:Inhibitory constant of the compound for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDihydrofolate reductase(Mus musculus (Mouse))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130313(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)copy SMILEScopy InChI
Affinity DataKi:  333nMAssay Description:Inhibitory constant of the compound for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9PTZPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143817(CHEMBL3758618)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239481(CHEMBL4061308)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143818(CHEMBL3759363)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239482(CHEMBL1683001)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239480(CHEMBL4074410)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239484(CHEMBL4103025)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143819(CHEMBL3759790)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239483(CHEMBL4088335)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239486(CHEMBL4062866)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143883(CHEMBL3759471)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239485(CHEMBL4060245)copy SMILEScopy InChI
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239480(CHEMBL4074410)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibitory activity against purine nucleoside phosphorylase (PNPase )More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239481(CHEMBL4061308)copy SMILEScopy InChI
Affinity DataIC50: 181nMAssay Description:Inhibition of DGTA1 in mouse C2C12 cells assessed as inhibition of triglyceride formation after 2 hrs by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239479(CHEMBL4088473)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143882(CHEMBL3759584)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239482(CHEMBL1683001)copy SMILEScopy InChI
Affinity DataIC50: 913nMAssay Description:Inhibition of DGTA1 in mouse C2C12 cells assessed as inhibition of triglyceride formation after 2 hrs by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239483(CHEMBL4088335)copy SMILEScopy InChI
Affinity DataIC50: 954nMAssay Description:Inhibition of DGTA1 in mouse C2C12 cells assessed as inhibition of triglyceride formation after 2 hrs by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143881(CHEMBL3758551)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50434377(CHEMBL2387002)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PDGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GGFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50337587(2-(2,6-dimethylphenyl)-N-(quinolin-2-yl)-1H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsome measured after 30 mins preincubation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VK1PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143880(CHEMBL3758531)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143829(CHEMBL3759017)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50434378(CHEMBL2386994)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PDGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GGFPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50337587(2-(2,6-dimethylphenyl)-N-(quinolin-2-yl)-1H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VK1PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143820(CHEMBL3759264)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50239480(CHEMBL4074410)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of DGAT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27XF2PubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50143822(CHEMBL3759291)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 6His-tagged DAGT1 expressed in fall armyworm Sf9 cells using diolein and oleoyl-CoA incubated for 30 mins by LC/MS/MS...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29ZSHPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50337588(CHEMBL1683000 | N-(quinolin-2-yl)-2-ortho-tolyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsome measured after 30 mins preincubation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VK1PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Global Discovery Chemistry

Curated by ChEMBL
LigandPNGBDBM50337588(CHEMBL1683000 | N-(quinolin-2-yl)-2-ortho-tolyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VK1PubMed