Compile Data Set for Download or QSAR
Found 126 with Last Name = 'kouketsu' and Initial = 'a'
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19136(CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19134(CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)copy SMILEScopy InChI
Affinity DataIC50: 36nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61JWXPubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19133(tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...)copy SMILEScopy InChI
Affinity DataIC50: 51nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)copy SMILEScopy InChI
Affinity DataIC50: 54nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19132(tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...)copy SMILEScopy InChI
Affinity DataIC50: 62nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19137(tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...)copy SMILEScopy InChI
Affinity DataIC50: 71nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475239(CHEMBL112234)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475246(CHEMBL320323)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)copy SMILEScopy InChI
Affinity DataIC50: 78nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475237(CHEMBL112105)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 81nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19138(tert-butyl N-[(1S)-1-(adamantan-1-ylcarbamoyl)-6-s...)copy SMILEScopy InChI
Affinity DataIC50: 82nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475250(CHEMBL113421)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50475236(CHEMBL113159)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19144((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223653(CHEMBL332246)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223653(CHEMBL332246)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054SZPubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19147(cyclohexyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19146(methyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19148(benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19142((2S)-N-cyclopentyl-2-(2-hydroxyacetamido)-7-sulfan...)copy SMILEScopy InChI
Affinity DataIC50: 150nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19131(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054SZPubMed
TargetHistone deacetylase 6(Mus musculus)
Nagoya City University

LigandPNGBDBM19140((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...)copy SMILEScopy InChI
Affinity DataIC50: 190nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223648(CHEMBL322504)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50223648(CHEMBL322504)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054SZPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28054SZPubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3P70PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19145((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19140((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration against histone deacetylase of HeLa cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Nagoya City University

LigandPNGBDBM19144((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CT6PubMed
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