Compile Data Set for Download or QSAR
Found 208 with Last Name = 'krick' and Initial = 'a'
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059435(CHEMBL3393498)copy SMILES
Affinity DataKi:  990nMAssay Description:Inhibition of human recombinant CYP3A4 in liver microsomes by mechanism based inhibition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM21363(12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...)copy SMILEScopy InChI
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of human recombinant CYP3A4 in liver microsomes by mechanism based inhibition assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059435(CHEMBL3393498)copy SMILES
Affinity DataIC50: 0.600nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)copy SMILES
Affinity DataIC50: 1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM47224(US9073917, 2-inventive)copy SMILES
Affinity DataIC50: 1nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059435(CHEMBL3393498)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059432(CHEMBL3393486)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059436(CHEMBL3393065)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059454(CHEMBL3393470)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059443(CHEMBL3393472)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059454(CHEMBL3393470)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059442(CHEMBL3393469)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059442(CHEMBL3393469)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase C(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059435(CHEMBL3393498)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora C (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059430(CHEMBL3393488)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM167510(US9073917, 7- comparative)copy SMILES
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)copy SMILES
Affinity DataIC50: 3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059443(CHEMBL3393472)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059433(CHEMBL3393485)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059446(CHEMBL3393475)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM167515(US9073917, 12- comparative)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)copy SMILES
Affinity DataIC50: 4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059442(CHEMBL3393469)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059450(CHEMBL3393479)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059445(CHEMBL3393474)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059442(CHEMBL3393469)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase C(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50004205(MK-045 | MK-0457 | TOZASERTIB | US9249124, VX680 |...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of aurora C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059431(CHEMBL3393487)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059461(CHEMBL3393462)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059456(CHEMBL3393467)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059440(CHEMBL3393490)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059447(CHEMBL3393476)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM167506(US9073917, 1-inventive)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)copy SMILES
Affinity DataIC50: 6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059593(CHEMBL3393484)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059445(CHEMBL3393474)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059449(CHEMBL3393478)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059448(CHEMBL3393477)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059592(CHEMBL3393494)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059450(CHEMBL3393479)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059590(CHEMBL3393495)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059446(CHEMBL3393475)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059439(CHEMBL3393491)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059593(CHEMBL3393484)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora A (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
SANOFI

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)copy SMILES
Affinity DataIC50: 8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993X4US Patent
TargetAurora kinase B(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50059451(CHEMBL3393482)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of poly-histidine tagged full length recombinant aurora B (unknown origin) assessed as phosphorylation of NuMA-histidine substrate by scin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T1559DPubMed
Displayed 1 to 50 (of 208 total ) | Next | Last >>
Jump to: