TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of flag-tagged HDAC4More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to human ER alphaMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of flag-tagged HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HDAC4 catalytic domain expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of flag-tagged HDAC4 expressed in HEK293 cells by Biomol assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMpH: 7.5 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 9.70nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 33nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 46nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 57nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of flag-tagged HDAC4 by Biomol assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Istituto di Ricerche di Biologia Molecolare
Curated by ChEMBL
Affinity DataIC50: 152nMAssay Description:Inhibition of flag-tagged HDAC4 by pull-down assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Binding affinity to ERalpha L384M/M421G mutantMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
IRBM (Merck Research Laboratories Rome)
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Binding affinity to human ER betaMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
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