Compile Data Set for Download or QSAR
Found 12 with Last Name = 'mandinova' and Initial = 'a'
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104010(DDR1-IN-2)copy SMILEScopy InChI
Affinity DataIC50: 47.6nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104009(DDR1-IN-1)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104010(DDR1-IN-2)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 337nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104009(DDR1-IN-1)copy SMILEScopy InChI
Affinity DataIC50: 413nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)copy SMILEScopy InChI
Affinity DataIC50: 675nMAssay Description:Tet inducible human DDR1 over-expressing U2OS was pre-treated by media containing each of the compound for 1 hour and treated by changing the media t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104010(DDR1-IN-2)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:The enzyme kinase assay was carried out using the Lanthascreen technology.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RWDPubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Broad Institute of Harvard and Massachusetts Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50249181(CHEMBL473392 | N-(4-chlorobenzyl)-2-((2R,6S,E)-5,1...)copy SMILEScopy InChI
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to N-terminal Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8D07PubMed
TargetSonic hedgehog protein(Homo sapiens (Human))
Broad Institute of Harvard and Massachusetts Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50323698(2-((3S,6S,12S,E)-12-amino-3-methyl-5,13-dioxo-1-ox...)copy SMILEScopy InChI
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to N-terminal Shh by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8D07PubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Massachusetts General Hospital and Harvard Medical School

LigandPNGBDBM104009(DDR1-IN-1)copy SMILEScopy InChI
Affinity DataEC50:  86nMAssay Description:The enzyme kinase assay was carried out using the Lanthascreen technology.More data for this Ligand-Target Pair