Compile Data Set for Download or QSAR
Found 244 with Last Name = 'marcinowicz' and Initial = 'a'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370555((1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibition of purified human IDO1 using varying levels of L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370452(2-(7-chloro-5H-imidazo[5,1-a]isoindol-5-yl)-1- cyc...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50138828(CHEMBL3752060 | US10233190, Example 1417)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370555((1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50138819(CHEMBL3753837 | US10233190, Example 1357)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370487(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370519(2-(4-fluorophenyl)-1-(4-(1-hydroxy-2-(5H- imidazo[...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370553((1S,4r)-4-((S)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370526(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370489(1-(4,4-difluorocyclohexyl)-2-(5H-imidazo[5,1- a]is...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370572(N-((1r,4r)-4-(1-hydroxy-2-(5H-imidazo[5,1- a]isoin...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370519(2-(4-fluorophenyl)-1-(4-(1-hydroxy-2-(5H- imidazo[...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370559(N-((1s,4s)-4-(1-hydroxy-2-(5H-imidazo[5,1- a]isoin...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370551((1S,4s)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50138827(CHEMBL3752711 | US10233190, Example 1418)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370487(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516665(CHEMBL4454031)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370455(US10233190, Example 1363 | tert-butyl 4-(1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370454(1-cyclopentyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)e...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50126144(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370542((1r,4r)-4-(2-(6-fluoro-5H-imidazo[5,1- a]isoindol-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370460(4-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)- 1-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370452(2-(7-chloro-5H-imidazo[5,1-a]isoindol-5-yl)-1- cyc...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370517(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516659(CHEMBL4562289)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516664(CHEMBL4461858)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516671(CHEMBL4579820)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370446(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1- phenylethano...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370568(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1-(pyridin-4- y...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516644(CHEMBL4563021)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370552((1R,4s)-4-((S)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516641(CHEMBL4455007)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370526(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370467(4-(2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)- 1-...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370424(2-(6-chloro-5H-imidazo[5,1-a]isoindol-5-yl)-1- cyc...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516645(CHEMBL4576216)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370506(US10233190, Example 1425 | cyclohexyl(4-(1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370506(US10233190, Example 1425 | cyclohexyl(4-(1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370504(1-(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol- 5-yl...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516646(CHEMBL4445081)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370451(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1- (tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370534(US10233190, Example 1460 | tert-butyl 3-(1-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370486(1-cyclohexyl-3-(5H-imidazo[5,1-a]isoindol-5- yl)pr...)copy SMILEScopy InChI
Affinity DataIC50: 906nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516647(CHEMBL4539142)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370456(1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370559(N-((1s,4s)-4-(1-hydroxy-2-(5H-imidazo[5,1- a]isoin...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM370489(1-(4,4-difluorocyclohexyl)-2-(5H-imidazo[5,1- a]is...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
NewLink Genetics Corporation

Curated by ChEMBL
LigandPNGBDBM50516663(CHEMBL4542931)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0QNZPubMed
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