TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:In vitro binding affinity of the compound against HIV protease was measuredMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2)More data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Binding affinity towards human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity towards human leukocyte elastase at 10e-7 MMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity towards human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-7 MMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 3nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 3nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 5nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 6nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Displacement of [18F]-FEH from MAO-A in mouse brain homogenate incubated for 60 mins by imaging analysisMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:In vitro binding affinity of the compound against HIV protease was measuredMore data for this Ligand-Target Pair
In DepthDetails
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 13nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 19nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 19nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 27nMAssay Description:Binding affinity towards human leukocyte elastase at 10e-7 MMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 29nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Monsanto Corporate Research
Monsanto Corporate Research
Affinity DataIC50: 35nMpH: 6.4 T: 2°CAssay Description:IC50 values for inhibition of recombinant HIV protease were determined using the spectrofluorometric assay, which utilized an intramolecularly quench...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [18F]-FEH from MAO-A in mouse brain homogenate incubated for 60 mins by imaging analysisMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measured (exp 2)More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-5 MMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Wisconsin-Madison
Curated by ChEMBL
University of Wisconsin-Madison
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:In vitro concentration of the compound required to inhibit 50% activity of HIV protease was measuredMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 82nMAssay Description:Displacement of [3H]PI-2620 from Tau in human brain homogenate incubated for 60 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibitory activity against human leukocyte elastase at 10e-8 MMore data for this Ligand-Target Pair
In DepthDetails
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