Compile Data Set for Download or QSAR
Found 156 with Last Name = 'remond' and Initial = 'a'
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.700nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS PatentDrugBank
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 2nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294915(US10112907, Example 00026)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM462294(US10766894, Compound TABLE 1.11 | US11203595, TABL...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM462294(US10766894, Compound TABLE 1.11 | US11203595, TABL...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294912(US10112907, Example 00021)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM147644(US10766894, Compound TABLE 1.6 | US11203595, TABLE...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM147644(US10766894, Compound TABLE 1.6 | US11203595, TABLE...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3JDHUS Patent
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK1 [866-1154](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetTyrosine-protein kinase JAK3 [811-1124](Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
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