Compile Data Set for Download or QSAR
Found 1292 with Last Name = 'rueger' and Initial = 'a'
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292202(CHEMBL382542 | N-(2-Aminomethyl-5-chloro-benzyl)-2...)copy SMILEScopy InChI
Affinity DataKi:  0.00100nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147818((2-[6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.00140nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147824(2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylam...)copy SMILEScopy InChI
Affinity DataKi:  0.00150nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292203(CHEMBL196030 | N-(5-Chloro-2-tetrazol-1-yl-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.00200nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133524(CHEMBL419773 | N-(2-Aminomethyl-5-chloro-benzyl)-2...)copy SMILEScopy InChI
Affinity DataKi:  0.00340nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P3119PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147793(CHEMBL323583 | N-(5-Chloro-2-tetrazol-1-yl-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0130nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337452(2-(4-chloro-2-((2-(6-methyl-2-oxo-3-(2-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.0150nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WS2PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147788(CHEMBL103874 | N-(5-Chloro-2-tetrazol-1-yl-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0180nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131480((S)-20-Benzyl-8,25-dichloro-18-methyl-12-oxa-1,4,1...)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147809(CHEMBL103342 | N-(5-Chloro-2-tetrazol-1-yl-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0330nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172842(CHEMBL198820 | [2-(5-Chloro-2-[1,2,4]triazol-1-yl-...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292196(CHEMBL195366 | N-(2-Aminomethyl-5-chloro-benzyl)-2...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122190(CHEMBL296737 | N-(5-chloro-2-ethylcarbamoylmethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P27005PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172826(CHEMBL426101 | [2-(5-Chloro-2-[1,2,4]triazol-1-yl-...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122190(CHEMBL296737 | N-(5-chloro-2-ethylcarbamoylmethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JQ0PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123490(CHEMBL143418 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.0420nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958J5PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133529(CHEMBL420682 | N-(2-Aminomethyl-5-chloro-benzyl)-2...)copy SMILEScopy InChI
Affinity DataKi:  0.0460nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P3119PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131460((S)-20-Benzyl-8,25-dichloro-12-oxa-1,4,18,21,23-pe...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131464((S)-20-Benzyl-8,25-dichloro-12,15-dioxa-1,4,18,21,...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133521(CHEMBL116202 | N-[2-(2-Amino-ethyl)-5-chloro-benzy...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P3119PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147812(2-{6-Chloro-3-[2,2-difluoro-2-(1-oxy-pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292200(2-[3-Chloro-6-(2,2-difluoro-2-pyridin-2-yl-ethylam...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172829(CHEMBL198735 | [2-(5-Chloro-2-[1,2,4]triazol-1-yl-...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131471((14Z,21S)-21-benzyl-8,26-dichloro-12,17-dioxa-1,4,...)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172841((2-{2-[2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-o...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50122183(CHEMBL431524 | N-(5-Chloro-2-ethylcarbamoylmethoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2348JQ0PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292189(2-[2-(3-Chloro-benzylamino)-2-hydroxy-ethyl]-6-(2,...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172839(CHEMBL197668 | [2-(5-Chloro-2-[1,2,4]triazol-1-yl-...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50088653(CHEMBL274152 | N-(6-Amino-2-methyl-pyridin-3-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.0840nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ07J2PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147801(CHEMBL102122 | N-(5-Chloro-2-[1,2,4]triazol-1-yl-b...)copy SMILEScopy InChI
Affinity DataKi:  0.0850nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126304(2-{6-Chloro-3-[2,2-difluoro-2-(1-oxy-pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  0.0870nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RC9PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131470((11S)-11-BENZYL-6-CHLORO-1,2,10,11,12,13,14,15,16,...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147821(2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylam...)copy SMILEScopy InChI
Affinity DataKi:  0.0960nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123504(CHEMBL142546 | N-((6-amino-2-methylpyridin-3-yl)me...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W958J5PubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50330326((4S,5R,6R)-5-Acetylamino-4-guanidino-6-((1R,3R)-1,...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of influenza B/Memphis/3/89 neuraminidaseMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50337453(2-(4-chloro-2-((2-(6-methyl-2-oxo-3-(2-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.125nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WS2PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133520(CHEMBL116258 | N-(2-Aminomethyl-5-chloro-benzyl)-2...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P3119PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131473((S)-20-Benzyl-8,25-dichloro-12-oxa-1,4,19,21,23-pe...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50371257(A-315675 | CHEMBL473062)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibition of influenza B/Memphis/3/89 neuraminidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7JHNPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172831(CHEMBL198978 | [2-(5-Chloro-2-[1,2,4]triazol-1-yl-...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147822(2-[6-Chloro-3-(2,2-difluoro-2-pyridin-2-yl-ethylam...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292201(CHEMBL372367 | N-(5-Chloro-2-tetrazol-1-yl-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  0.140nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96C6PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50147810(CHEMBL100854 | N-(5-Chloro-2-[1,2,4]triazol-1-yl-b...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q270826BPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172845((2-{2-[2-(5-Chloro-2-[1,2,4]triazol-1-yl-benzyl)-o...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibitory constant against thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z153PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126303(2-{6-Chloro-3-[2,2-difluoro-2-(1-oxy-pyridin-2-yl)...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RC9PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131458((14E,21S)-21-benzyl-8,26-dichloro-12,17-dioxa-1,4,...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126309(CHEMBL29744 | N-(3-Bromo-benzyl)-2-{6-chloro-3-[2,...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2833RC9PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372032(CHEMBL270649)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P27005PubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126493(2-(3-Amino-4-cyclobutylmethanesulfonyl-6-methyl-2-...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q8CPubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131466((S)-19-Benzyl-8,24-dichloro-12-oxa-1,4,17,20,22-pe...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0V2PPubMed
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