Compile Data Set for Download or QSAR
Found 60 with Last Name = 'telliez' and Initial = 'a'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50000829(6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156577(1-(4-aminosulfonylphenyl)-3-[3-fluoro-5-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156584(1-(4-methanesulfonylphenyl)-3-[(3,4,5-trimethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50110484(3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156594(3-[(3-fluoro-5-methoxy)phenoxymethyl]-1-(4-methane...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156580(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156590(1-(4-methanesulfonylphenyl)-3-[(3,4-methylenedioxy...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156585(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156587(3-[(5-cyano-3-fluoro)phenoxymethyl]-1-(4-methanesu...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156582(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156582(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156579(1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156583(1-(4-methanesulfonylphenyl)-3-[(3,4-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156586(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156591(1-(4-methanesulfonylphenyl)-3-[(3-nitro)phenoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156577(1-(4-aminosulfonylphenyl)-3-[3-fluoro-5-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156580(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156581(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156579(1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytet...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156588(1-(4-trifluoromethoxyphenyl)-3-[3-fluoro-5-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156589(1-(4-chlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156588(1-(4-trifluoromethoxyphenyl)-3-[3-fluoro-5-(4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156592(1-(4-methanesulfonylphenyl)-3-[(3,5-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156593(3-[(3-ethoxy)phenoxymethyl]-1-(4-methanesulfonylph...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156578(1-(4-methanesulfonylphenyl)-3-[3-(4-morpholino)phe...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156586(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156589(1-(4-chlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156585(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 960nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156585(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156586(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156589(1-(4-chlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahy...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156582(3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)pheno...)copy SMILEScopy InChI
Affinity DataIC50: 7.14E+3nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156590(1-(4-methanesulfonylphenyl)-3-[(3,4-methylenedioxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156591(1-(4-methanesulfonylphenyl)-3-[(3-nitro)phenoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156584(1-(4-methanesulfonylphenyl)-3-[(3,4,5-trimethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156583(1-(4-methanesulfonylphenyl)-3-[(3,4-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156578(1-(4-methanesulfonylphenyl)-3-[3-(4-morpholino)phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156587(3-[(5-cyano-3-fluoro)phenoxymethyl]-1-(4-methanesu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156594(3-[(3-fluoro-5-methoxy)phenoxymethyl]-1-(4-methane...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156593(3-[(3-ethoxy)phenoxymethyl]-1-(4-methanesulfonylph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156592(1-(4-methanesulfonylphenyl)-3-[(3,5-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156590(1-(4-methanesulfonylphenyl)-3-[(3,4-methylenedioxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156584(1-(4-methanesulfonylphenyl)-3-[(3,4,5-trimethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Université de Lille 2

Curated by ChEMBL
LigandPNGBDBM50156592(1-(4-methanesulfonylphenyl)-3-[(3,5-dimethoxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2V01PubMed
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