Compile Data Set for Download or QSAR
Found 88 with Last Name = 'turner' and Initial = 'a'
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238166(US10017502, Example 7 | US9394291, 7)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238166(US10017502, Example 7 | US9394291, 7)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404277(US10017502, Example 8b)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238167(US10017502, Example 8 | US9394291, 8 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404271(US10017502, Example 6a)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetProteasome subunit beta type-8(Mus musculus)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50201035(CHEMBL3907636)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of chymotrypsin like activity of mouse spleen 20S proteasome beta5i subunit using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2417019PubMed
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238161(US10017502, Example 5a | US9394291, 5a)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238161(US10017502, Example 5a | US9394291, 5a)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetProteasome subunit beta type-8(Mus musculus)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of chymotrypsin like activity of mouse spleen 20S proteasome beta5i subunit using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238167(US10017502, Example 8 | US9394291, 8 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 40nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238167(US10017502, Example 8 | US9394291, 8 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 58nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 82nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetProteasome subunit beta type-8(Mus musculus)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50201038(CHEMBL3898621)copy SMILEScopy InChI
Affinity DataIC50: 113nMAssay Description:Inhibition of chymotrypsin like activity of mouse spleen 20S proteasome beta5i subunit using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2417019PubMed
TargetProteasome subunit beta type-8(Mus musculus)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50201036(CHEMBL3972546)copy SMILEScopy InChI
Affinity DataIC50: 118nMAssay Description:Inhibition of chymotrypsin like activity of mouse spleen 20S proteasome beta5i subunit using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2417019PubMed
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404265(US10017502, Example 4a)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238159(US10017502, Example 4b | US9394291, 4a)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238158(US10017502, Example 4 | US9394291, 4)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238158(US10017502, Example 4 | US9394291, 4)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404258(US10017502, Example 2a)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238152(US10017502, Example 2 | US9394291, 2 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 230nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404265(US10017502, Example 4a)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238159(US10017502, Example 4b | US9394291, 4a)copy SMILEScopy InChI
Affinity DataIC50: 240nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404263(2-{(3S or 3R)-7-Fluoro-4-[(3-oxo-3,4-dihydro-2H-1,...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238155(US10017502, Example 3 | US9394291, 3 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 270nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238155(US10017502, Example 3 | US9394291, 3 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238155(US10017502, Example 3 | US9394291, 3 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 480nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetProteasome subunit beta type-8(Mus musculus)
The University of Adelaide

Curated by ChEMBL
LigandPNGBDBM50201037(CHEMBL3978175)copy SMILEScopy InChI
Affinity DataIC50: 483nMAssay Description:Inhibition of chymotrypsin like activity of mouse spleen 20S proteasome beta5i subunit using Suc-Leu-Leu-Val-Tyr-AMC as substrate preincubated for 15...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2417019PubMed
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238158(US10017502, Example 4 | US9394291, 4)copy SMILEScopy InChI
Affinity DataIC50: 740nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238158(US10017502, Example 4 | US9394291, 4)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
TargetEcdysone receptor(Lucilia cuprina)
CSIRO Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326776(2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238151(US10017502, Example 1 | US9394291, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238151(US10017502, Example 1 | US9394291, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404276(US10017502, Example 8a)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238167(US10017502, Example 8 | US9394291, 8 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238152(US10017502, Example 2 | US9394291, 2 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238152(US10017502, Example 2 | US9394291, 2 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238163(US10017502, Example 6 | US9394291, 6 | US9394291, ...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM404273(US10017502, Example 6b)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238151(US10017502, Example 1 | US9394291, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238151(US10017502, Example 1 | US9394291, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMpH: 7.5Assay Description:Test A2: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238162(US10017502, Example 5b | US9394291, 5b)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Test A1 and A2: In order to identify binding to the human MR LBD a scintillation proximity assay (SPA) was adapted to the 384-well format. The MR-LBD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862JSVUS Patent
TargetMineralocorticoid receptor [729-984](Homo sapiens (Human))
AstraZeneca AB

US Patent
LigandPNGBDBM238162(US10017502, Example 5b | US9394291, 5b)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMpH: 7.5Assay Description:Test A1: Briefly, in Test A1 the assay was run in 384 well format in 10 mM Tris-HCl, pH 7.5, 0.5 mM EDTA 20 mM NaMoO4, 0.1 mM DTT and 10% glycerol at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125RJSUS Patent
TargetEcdysone receptor(Lucilia cuprina)
CSIRO Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326777((2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydrox...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6D43PubMed
TargetEcdysone receptor(Lucilia cuprina)
CSIRO Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326770(4-isobutyl-5-methylene-2-oxo-1-(2,4,5-trichlorophe...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6D43PubMed
TargetEcdysone receptor(Lucilia cuprina)
CSIRO Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326767(4-butyl-1-(2-tert-butyl-5-chlorophenyl)-5-methylen...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6D43PubMed
TargetEcdysone receptor(Lucilia cuprina)
CSIRO Molecular and Health Technologies

Curated by ChEMBL
LigandPNGBDBM50326755(1-(2,5-di-tert-butylphenyl)-4-methyl-5-methylene-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Binding affinity to Lucilia cuprina recombinant ecdysone receptor ligand binding domain after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6D43PubMed
Displayed 1 to 50 (of 88 total ) | Next | Last >>
Jump to: