Compile Data Set for Download or QSAR
Found 218 with Last Name = 'villasenor' and Initial = 'a'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15774((2R)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15773((2S)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15776(2-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15775(1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15772(4-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15756(3-(4-Fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151775(3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-2-me...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15764(3-(4-Fluorophenyl)-1-methoxy-ethyl-2-pyridin-4-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15765(3-(4-Fluorophenyl)-1-ethyl-2-pyridin-4-yl-1H-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM13531(4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151760(3-(4-Fluoro-phenoxy)-6-methanesulfonyl-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15759(4,7 Diazaindole 22 | 4-[7-(4-fluorophenyl)-5H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 53nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15763(3-(4-Fluoro-phenyl)-1-methoxy-2-pyridin-4-yl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 68nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151758(3-(2-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151763(3-(4-Fluoro-benzyl)-6-methanesulfonyl-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15762(3-(4-Fluorophenyl-2-(pyridin-4yl)furo[3,2-b]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 86nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15766(3-(4-Fluorophenyl)-1-methyl-2-pyridin-4-yl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 98nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151762(3-(2,4-Dichloro-phenoxy)-6-methanesulfonyl-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151765(3-(2,4-Difluoro-phenoxy)-6-methanesulfonyl-2-methy...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151768(3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15767(1-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 172nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15744(1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262376(6-((7-(3-chlorobenzyl)benzofuran-5-yl)methyl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15768(3-(4-Fluorophenyl)-1-morpholinoethyl-2-pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 185nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151759(6-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151773(4-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15769(3-(4-Fluorophenyl)-1-pyrrolidinoethyl-2-pyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 217nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6QHTPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15749(1-[2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151782(3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151766(3-(4-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151783(6-Methanesulfonyl-3-(4-methoxy-benzyl)-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151767(3-(4-Chloro-phenoxy)-6-methanesulfonyl-2-methyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15743(1-(2,4-difluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151770(3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15745(1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yloxy)phen...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151776(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151776(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262377(6-((7-(3-chlorophenoxy)benzofuran-5-yl)methyl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151784(CHEMBL184022 | [3-(4-Fluoro-phenylsulfanyl)-6-meth...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151774(6-Methanesulfonyl-3-(4-methoxy-phenylsulfanyl)-2-m...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151768(3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15750(4-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50262375(6-((7-(3-chlorobenzoyl)benzofuran-5-yl)methyl)pyri...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8FC6PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151779((4-Fluoro-phenyl)-(6-methanesulfonyl-2-methyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15754((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151772(3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15740(1-(4-fluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carb...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15748(1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50151777(3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q228072SPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

LigandPNGBDBM15746(2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23776ZNPubMed
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