Compile Data Set for Download or QSAR
Found 1423 with Last Name = 'yau' and Initial = 'a'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326858(CHEMBL1254556 | N-((3R,4R,5S,6R)-2,4-bis(4-chlorob...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326859(CHEMBL1254630 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326860(CHEMBL1254711 | N-((3R,4R,5S,6R)-2-(4-chlorobenzyl...)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326861(CHEMBL1254796 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326862(4-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...)copy SMILEScopy InChI
Affinity DataKi:  5.10E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326863(3-(diaminomethyleneamino)-N-((3R,4R,5S,6R)-5-hydro...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326864(CHEMBL1254883 | N-((3R,4R,5S,6R)-4-(4-chlorobenzyl...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [I125I]MCH from human MCH1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM109086(US10793535, Cmpd ID 727 | US8604016, 670 | US99382...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404825(1-(4-{6-[2-(pyridin-2- yl)acetamido]pyridazin-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150818(CHEMBL3774575)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150821(CHEMBL3775251)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150820(CHEMBL3774933)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404911((R)-1-(2-fluoro-4-(6-(2-(4-(3- (trifluoromethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150758(CHEMBL3775901)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404848(N-methyl-1-{4-[6-(2-{4-[3- (trifluoromethoxy)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150822(CHEMBL3775348)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150756(CHEMBL3774766)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150819(CHEMBL3774542)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404666(US10344025, Example 5 | US11370786, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405185(N-(pyridin-2-ylmethyl)-1-[4-(6-{2-[3- (trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405183(N-(cyanomethyl)-1-[4-(6-{2-[3- (trifluoromethoxy)p...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50548670(CHEMBL4741924)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of GLS1 in human A549 cells assessed as reduction in conversion of glutamine to glutamate measured after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404924((R)-1-(2-fluoro-4-(6-(2-(6-methyl-4- (trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50548671(CHEMBL4797071)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405207(N-(2-methoxyethyl)-1-[4-(6-{2-[3- (trifluoromethox...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404928((R)-1-(4-(6-(2-(4-(3,3- difluorocyclobutoxy)pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50400050(CHEMBL2177757 | US10793535, Cmpd ID 1 | US11191732...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM50548670(CHEMBL4741924)copy SMILES
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404910((R)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404813(N-methyl-1-[4-(6-{2-[3- (trifluoromethoxy)phenyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404866(N-methyl-1-(4-(6-(2-(4- (trifluoromethyl)pyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150812(CHEMBL3775853 | US10702504, Compound D)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404915((R)-1-(2-fluoro-4-(6-(2-(4- (trifluoromethyl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404917(1-(4-(6-(2-(4-(3,3- difluorocyclobutoxy)pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404881(N-methyl-1-(4-(6-(2-(4-(2,2,2- trifluoroethoxy)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326854((Naphth-2-yl)methyl-2-(4'-Aminobutyrylamido)-3-O-(...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150811(CHEMBL3775073)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150808(CHEMBL3774507 | US10702504, Compound C)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150757(CHEMBL3774770)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26975F4PubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404912((S)-1-(2-fluoro-4-(6-(2-(pyridin-2- yl)acetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405197(N-methyl-1-(4-{6-[2-(pyridin-3- yl)acetamido]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326872(CHEMBL1254140 | Naphth-2-yl)methyl-2-(4'-Aminobuty...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326878((2R,3S,5R)-5-(3-aminopropylamino)-4-(4-chlorobenzy...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM404823(N-methyl-1-(4-{6-[2-(pyridin-2- yl)acetamido]pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405184(N-(2-hydroxyethyl)-1-[4-(6-{2-[3- (trifluoromethox...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human GLS1 using glutamine as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8WGCPubMed
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
The University of Texas MD Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50150761(CHEMBL3775689)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Alchemia Ltd

Curated by ChEMBL
LigandPNGBDBM50326879((2R,3S,5R)-5-(2-aminoethylamino)-2-(methoxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]iodotyrosyl from human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC03QKPubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405060(1-[2-fluoro-4-(4-{2-[2-fluoro-5- (trifluoromethoxy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HQCUS Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405061(1-(2-fluoro-4-{4-[2-(6-methylpyridin- 3-yl)acetami...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HQCUS Patent
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))TBA
LigandPNGBDBM405062(1-[2-fluoro-4-(4-{2-[3- (trifluoromethoxy)phenyl]a...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2765HQCUS Patent
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