Compile Data Set for Download or QSAR
Found 241 with Last Name = 'boullay' and Initial = 'ab'
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271572(1-[4-Chlorophenylcarbonyl]-4-[4-(pyridin-4-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271622(1-[4-Chlorophenylsulfonyl]-4-[4-(4-methylpiperazin...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118668(CHEMBL3617086)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118637(CHEMBL3617084)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118669(CHEMBL3617083)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271571(1-[4-Chlorophenylsulfonyl]-4-[4-(pyridin-4-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)copy SMILEScopy InChI
Affinity DataIC50: 15.5nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118672(CHEMBL3617082)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271621(1-[4-(Trifluoromethoxy)phenylcarbonyl]-4-[4-(dimet...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118524(CHEMBL3617080)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118523(CHEMBL3617079)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118588(CHEMBL3617095)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271529(CHEMBL483314 | N-[2-(4-(4-Dimethylaminomethylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)copy SMILEScopy InChI
Affinity DataIC50: 28.4nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB2541PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365264(CHEMBL1738926)copy SMILEScopy InChI
Affinity DataIC50: 29.9nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd2 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB2541PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118610(CHEMBL3617102)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271623(1-[4-Chlorophenylcarbonyl]-4-[4-(imidazol-1-yl)phe...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271620(1-[4-Chlorophenylsulfonyl]-4-[4-(dimethylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBromodomain-containing protein 2(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataIC50: 32.5nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd2 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB2541PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataIC50: 36.1nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd4 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118607(CHEMBL3617098)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271619(1-[4-Chlorophenylcarbonyl]-4-[4-(dimethylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBromodomain-containing protein 3(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)copy SMILEScopy InChI
Affinity DataIC50: 42.4nMAssay Description:Displacement of tetra-acetylated H4 peptide from human Brd3 bromodomain BD12 after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB2541PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173927(CHEMBL3808902)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118669(CHEMBL3617083)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118637(CHEMBL3617084)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118521(CHEMBL3617077)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118522(CHEMBL3617078)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173927(CHEMBL3808902)copy SMILEScopy InChI
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118665(CHEMBL3617085)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATc (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118668(CHEMBL3617086)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118524(CHEMBL3617080)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetLanosterol synthase(Homo sapiens (Human))
Laboratoire GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50271530(CHEMBL483918 | N-[2-(4-(4-((Pyrolidin-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61K14PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173926(CHEMBL3808971)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173928(CHEMBL3809839)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173926(CHEMBL3808971)copy SMILEScopy InChI
Affinity DataIC50: 63.1nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173928(CHEMBL3809839)copy SMILEScopy InChI
Affinity DataIC50: 63.1nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118578(CHEMBL3617094)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118672(CHEMBL3617082)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173923(CHEMBL3810317)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118589(CHEMBL3617096)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173922(CHEMBL3809282)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173923(CHEMBL3810317)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50173922(CHEMBL3809282)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes using L-Serine and L-Leucine as substrate after overnight incubation by reverse-phase ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W097V6PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118609(CHEMBL3617100)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118520(CHEMBL3617075)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118523(CHEMBL3617079)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50118522(CHEMBL3617078)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of BCATm in differentiated primary human adipocytes assessed as remaining leucine level by reversed phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43VWKPubMed
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