Compile Data Set for Download or QSAR
Found 22 with Last Name = 'lopes' and Initial = 'ab'
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human CHK2 kinase expressed in insect Sf21 cells using phospho-CREBtide as substrate at 30 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08ZVPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396783(CHEMBL2172710)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant IKK-alpha expressed in insect Sf21 cells using phospho-Ulight-IkappaB-alpha as substrate at 30 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08ZVPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396783(CHEMBL2172710)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396784(CHEMBL2172734)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396783(CHEMBL2172710)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396784(CHEMBL2172734)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396782(CHEMBL2172731)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396784(CHEMBL2172734)copy SMILEScopy InChI
Affinity DataIC50: 159nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396785(CHEMBL2172707)copy SMILEScopy InChI
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 162nMAssay Description:Inhibition of human recombinant PDE4AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396783(CHEMBL2172710)copy SMILEScopy InChI
Affinity DataIC50: 206nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396785(CHEMBL2172707)copy SMILEScopy InChI
Affinity DataIC50: 231nMAssay Description:Inhibition of human recombinant PDE4BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant IKK-beta expressed in insect Sf21 cells using phospho-Ulight-IkappaB-alpha as substrate at 30 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08ZVPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396784(CHEMBL2172734)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396785(CHEMBL2172707)copy SMILEScopy InChI
Affinity DataIC50: 622nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 622nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM14769(6-(3,4-Dimethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50396785(CHEMBL2172707)copy SMILEScopy InChI
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of human recombinant PDE4CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC11TCPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Universidade Federal do Rio de Janeiro

Curated by ChEMBL
LigandPNGBDBM50340790((E)-N-(4-nitrobenzylidene)-2-naphthohydrazide | CH...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant IKK-beta expressed in insect Sf21 cells using phospho-Ulight-IkappaB-alpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M08ZVPubMed