Compile Data Set for Download or QSAR
Found 112 with Last Name = 'singh' and Initial = 'ab'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93118(PTP1B Inhibitor, 19)copy SMILEScopy InChI
Affinity DataKi:  2.50E+4nM IC50: 6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  2.71E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  2.87E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93109(PTP1B Inhibitor, 5)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nM IC50: 7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93111(PTP1B Inhibitor, 7)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nM IC50: 8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  3.41E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  3.42E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataKi:  3.63E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266160(2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataKi:  4.44E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93113(PTP1B Inhibitor, 11)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nM IC50: 6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93112(PTP1B Inhibitor, 10)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nM IC50: 6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487368(CHEMBL2259740)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487364(CHEMBL2259741)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93110(PTP1B Inhibitor, 6)copy SMILEScopy InChI
Affinity DataKi:  5.60E+4nM IC50: 9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93116(PTP1B Inhibitor, 14)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nM IC50: 8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487366(CHEMBL2259730)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93117(PTP1B Inhibitor, 15)copy SMILEScopy InChI
Affinity DataKi:  1.35E+5nM IC50: 1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487365(CHEMBL2259731)copy SMILEScopy InChI
Affinity DataKi:  1.35E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93115(PTP1B Inhibitor, 13)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nM IC50: 2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487367(CHEMBL2259743)copy SMILEScopy InChI
Affinity DataKi:  1.50E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM93114(PTP1B Inhibitor, 12)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nM IC50: 4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50487369(CHEMBL2259742)copy SMILEScopy InChI
Affinity DataKi:  1.70E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZMG
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266159(CHEMBL506882 | Diethyl-[2-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataKi:  3.55E+5nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346150(5-(2-(2-(1H-pyrrol-1-yl)ethoxy)-4-methoxyphenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346150(5-(2-(2-(1H-pyrrol-1-yl)ethoxy)-4-methoxyphenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266161(2-[4-(2-Piperidine-1-yl-ethoxy)-phenyl]-naphtho[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346151(4-(2-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)e...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266162(Butyl-methyl-[2-(4-naphtho[1,2-d]oxazol-2-yl-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346151(4-(2-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)e...)copy SMILEScopy InChI
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346148(CHEMBL1783773 | N,N-diethyl-2-(5-methoxy-2-(3-phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346148(CHEMBL1783773 | N,N-diethyl-2-(5-methoxy-2-(3-phen...)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346166(1-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346165(1-(5-methoxy-2-(3-phenylisoxazol-5-yl)phenoxy)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J966QVPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266231(CHEMBL510460 | Dimethyl-[3-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,

LigandPNGBDBM50266158(CHEMBL510225 | Dimethyl-[2-(4-naphtho[1,2-d]oxazol...)copy SMILEScopy InChI
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN1602PubMed
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