TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 2.50E+4nM IC50: 6.27E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 2.51E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 2.71E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 2.75E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 2.87E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.00E+4nM IC50: 7.00E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.40E+4nM IC50: 8.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.41E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.42E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.50E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.63E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.70E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.05E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.44E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.80E+4nM IC50: 6.70E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.80E+4nM IC50: 6.90E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 4.80E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 5.60E+4nM IC50: 9.10E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 6.30E+4nM IC50: 8.80E+4nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 6.30E+4nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.35E+5nM IC50: 1.65E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.35E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.50E+5nM IC50: 2.75E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.50E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.70E+5nM IC50: 4.85E+5nMpH: 7.0Assay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 1.70E+5nMAssay Description:The effect of the test compounds on PTP1B was studied by preincubating the test compound with enzyme in the reaction system for 10 min and determinin...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataKi: 3.55E+5nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 2.97E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute,
Central Drug Research Institute,
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair