Compile Data Set for Download or QSAR
Found 37 with Last Name = 'debaillie' and Initial = 'ac'
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247164(CHEMBL4101901)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204012(CHEMBL3955132)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247166(CHEMBL4082711)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247163(CHEMBL4059614)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247156(CHEMBL4101472)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247167(CHEMBL4097527)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247162(CHEMBL4075819)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247165(CHEMBL4077366)copy SMILEScopy InChI
Affinity DataKi:  102nMAssay Description:Competitive displacement of [3H]-TAK-875 from full length human recombinant GPR40 expressed in HEK293 cell membranes after 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247162(CHEMBL4075819)copy SMILEScopy InChI
Affinity DataEC50:  95nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247167(CHEMBL4097527)copy SMILEScopy InChI
Affinity DataEC50:  98nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247166(CHEMBL4082711)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247167(CHEMBL4097527)copy SMILEScopy InChI
Affinity DataEC50:  1nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204012(CHEMBL3955132)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataEC50:  108nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247162(CHEMBL4075819)copy SMILEScopy InChI
Affinity DataEC50:  1.49E+3nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247165(CHEMBL4077366)copy SMILEScopy InChI
Affinity DataEC50:  562nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247163(CHEMBL4059614)copy SMILEScopy InChI
Affinity DataEC50:  216nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247156(CHEMBL4101472)copy SMILEScopy InChI
Affinity DataEC50:  68nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247166(CHEMBL4082711)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetMelanocortin receptor 4(Rattus norvegicus)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50204020(CHEMBL3927519)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247167(CHEMBL4097527)copy SMILEScopy InChI
Affinity DataEC50:  166nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247163(CHEMBL4059614)copy SMILEScopy InChI
Affinity DataEC50:  443nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247156(CHEMBL4101472)copy SMILEScopy InChI
Affinity DataEC50:  301nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247166(CHEMBL4082711)copy SMILEScopy InChI
Affinity DataEC50:  67nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247165(CHEMBL4077366)copy SMILEScopy InChI
Affinity DataEC50:  681nMAssay Description:Agonist activity at human PK-tagged GPR40 expressed in HEK293 cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 % ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247164(CHEMBL4101901)copy SMILEScopy InChI
Affinity DataEC50:  8nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50200369(CHEMBL3915620)copy SMILEScopy InChI
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247163(CHEMBL4059614)copy SMILEScopy InChI
Affinity DataEC50:  9nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247165(CHEMBL4077366)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247156(CHEMBL4101472)copy SMILEScopy InChI
Affinity DataEC50:  72nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50247162(CHEMBL4075819)copy SMILEScopy InChI
Affinity DataEC50:  117nMAssay Description:Agonist activity at human GPR40 receptor expressed in HEK293 cells assessed as increase in intracellular calcium flux after 2.5 hrs measured over 3 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39K5PubMed