Compile Data Set for Download or QSAR
Found 38 with Last Name = 'guinn' and Initial = 'ac'
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127407(5-{2-[4-(2-Biphenyl-2-yl-2-hydroxy-acetylamino)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127427((S)-4-[(S)-2-((S)-2-{(S)-4-[2-((1S,2S)-2-Acetylami...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127433(5-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127401(5-{2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ace...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127400(4-[2-(2-{4-[2-(2-Bromo-phenyl)-2-hydroxy-acetylami...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127425(3-[(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127426(4-[(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127430(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127419(CHEMBL51188 | {3-[(2-{4-[2-(2-tert-Butoxycarbonyla...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127410(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127404(5-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127414(4-[2-(2-{4-[2-(2-Benzyloxy-phenyl)-2-hydroxy-acety...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127431(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127435(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127436(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127408(4-(2-{2-[4-(4-Butoxy-benzoylamino)-3-hydroxy-6-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127422(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127421(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127402(3-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127409(4-[(2-{4-[2-(2-Bromo-phenyl)-2-hydroxy-acetylamino...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127417(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127424(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-(2-{2-[3-h...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127403(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127434(4-(2-{4-[2-(2-tert-Butoxycarbonylamino-3-methyl-bu...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127416(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127432(4-({2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ac...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127415(5-{1-[2-(1-{1-[3-Carboxy-1-(1-carboxy-2-phenyl-eth...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127405(4-(2-{2-[4-(2-Biphenyl-4-yl-acetylamino)-3-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127413(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-h...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127411(CHEMBL50827 | [1-(1-{1-[1-Hydroxy-2-(1-hydroxycarb...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127423((1-{1-[1-(2-{1-[(Benzo[1,3]dioxol-5-ylmethyl)-carb...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127412((1-{1-[1-(1-Hydroxy-2-{2-methyl-1-[(pyridin-4-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127406(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-{2-[2-(3-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127428(4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{4-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127429(5-{2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-ace...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127437(CHEMBL52225 | [1-(1-{1-[2-(1-Butylcarbamoyl-2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127418(CHEMBL49711 | {1-[1-(1-{2-[1-(Cyclohexylmethyl-car...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50127420(CHEMBL298141 | [1-(1-{1-[2-(1-Cyclohexylcarbamoyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human beta-secretase (BACE) in MBP-C125 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6RMKPubMed