Compile Data Set for Download or QSAR
Found 50 with Last Name = 'tabaka' and Initial = 'ac'
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of the dual specificity kinase MEK-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMedMMDB
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of the dual specificity kinase MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMedMMDB
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:AP-1 suppression activity using freshly prepared DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:AP-1 suppression activity using one month old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072154(2,3-Bis-[1-amino-1-(2-hydroxy-phenylsulfanyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072163(2,3-Bis-[1-amino-1-(thiophen-2-ylsulfanyl)-meth-(Z...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:AP-1 suppression activity using one week old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072154(2,3-Bis-[1-amino-1-(2-hydroxy-phenylsulfanyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072166(2,3-Bis-[1-amino-1-(4-hydroxy-phenylsulfanyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072151(2,3-Bis-[1-amino-1-(4-amino-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:AP-1 suppression activity using two months old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMedMMDB
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072148(2,3-Bis-[3H-benzothiazol-(2Z)-ylidene]-succinonitr...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072162(2,3-Bis-[1-amino-1-(2-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072164(2,3-Bis-[1-amino-1-phenylsulfanyl-meth-(Z)-ylidene...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072156(2,3-Bis-[1-amino-1-(2-fluoro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072150(2,3-Bis-[1-amino-1-(2-bromo-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072163(2,3-Bis-[1-amino-1-(thiophen-2-ylsulfanyl)-meth-(Z...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072144(2-Amino-5-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072157(2,3-Bis-[1-amino-1-(3-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072146(CHEMBL316635 | N-[3,4-Dicyano-5-(naphthalen-2-ylsu...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072161(2,3-Bis-[1-amino-1-o-tolylsulfanyl-meth-(Z)-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072160(2,5-Bis-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072158(2,3-Bis-[1-amino-1-(1-amino-naphthalen-2-ylsulfany...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072152(2,3-Bis-[1-amino-1-(4-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of the dual specificity kinase MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMedMMDB
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072159(2,3-Bis-[1-amino-1-(2,6-dichloro-phenylsulfanyl)-m...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072165(2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072155(2,3-Bis-[1-amino-1-(2-methoxy-phenylsulfanyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072149(2,3-Bis-[1-amino-1-(3-amino-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072159(2,3-Bis-[1-amino-1-(2,6-dichloro-phenylsulfanyl)-m...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072162(2,3-Bis-[1-amino-1-(2-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072156(2,3-Bis-[1-amino-1-(2-fluoro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072150(2,3-Bis-[1-amino-1-(2-bromo-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072146(CHEMBL316635 | N-[3,4-Dicyano-5-(naphthalen-2-ylsu...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072151(2,3-Bis-[1-amino-1-(4-amino-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072164(2,3-Bis-[1-amino-1-phenylsulfanyl-meth-(Z)-ylidene...)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072161(2,3-Bis-[1-amino-1-o-tolylsulfanyl-meth-(Z)-yliden...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072145(2-Amino-5-(2-amino-phenylsulfanyl)-1H-pyrrole-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+4nMAssay Description:Non-competitive inhibition of the dual specificity kinase MEKMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072155(2,3-Bis-[1-amino-1-(2-methoxy-phenylsulfanyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of the dual specificity kinase MEK-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072149(2,3-Bis-[1-amino-1-(3-amino-phenylsulfanyl)-meth-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072157(2,3-Bis-[1-amino-1-(3-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072165(2-[1-Amino-1-(2-amino-phenylsulfanyl)-meth-(Z)-yli...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072152(2,3-Bis-[1-amino-1-(4-chloro-phenylsulfanyl)-meth-...)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072147((2Z,3Z)-2,3-bis(amino(2-aminophenylthio)methylene)...)copy SMILEScopy InChI
Affinity DataIC50: 2.48E+4nMAssay Description:AP-1 suppression activity using six months old DMSO stockMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072144(2-Amino-5-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072145(2-Amino-5-(2-amino-phenylsulfanyl)-1H-pyrrole-3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.62E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072160(2,5-Bis-(naphthalen-2-ylsulfanyl)-1H-pyrrole-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed
TargetDual specificity mitogen-activated protein kinase kinase 1/2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50072148(2,3-Bis-[3H-benzothiazol-(2Z)-ylidene]-succinonitr...)copy SMILEScopy InChI
Affinity DataIC50: 4.25E+4nMAssay Description:Ability to antagonise AP-1 transcriptional activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2HNNPubMed