Compile Data Set for Download or QSAR
Found 30 with Last Name = 'busch' and Initial = 'ae'
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM39687((2E)-1-ethyl-2-[(1-ethyl-2-quinolin-1-iumyl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50420192(CHEMBL2074851)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50420181(CHEMBL2074704)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM81945(CAS_39484 | CHEMBL105891 | CHEMBL108926 | CHEMBL27...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50367247(QUININE | Quinamm | Quinsan | cid_3034034)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMedDrugBank
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50420216(MEPIPERPHENIDOL BROMIDE)copy SMILEScopy InChI
Affinity DataKi:  4.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMedDrugBank
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM39344(4-amino-N-[2-(diethylamino)ethyl]benzamide;hydroch...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMedDrugBank
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50079455(CHEMBL46486 | tetramethylammonium)copy SMILEScopy InChI
Affinity DataKi:  1.80E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50420177(NICOTINYL METHYLAMIDE)copy SMILEScopy InChI
Affinity DataKi:  2.66E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50420217(METIPRENALINE)copy SMILEScopy InChI
Affinity DataKi:  5.70E+5nMAssay Description:TP_TRANSPORTER: inhibition of TEA uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R2148RPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106236((3R,4S)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50099582((3R,4S)N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106233(CHEMBL124308 | N-(6-Benzyloxy-3-hydroxy-2,2-dimeth...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106231(CHEMBL340910 | N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106232(CHEMBL125307 | N-(6-Butoxy-3-hydroxy-2,2-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106237((3S,4R)-Ethanesulfonic acid (6-benzyloxy-3-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106234((3S,4R)-(+)-N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-tri...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106228((3R,4S)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106235(CHEMBL124810 | N-(3-Hydroxy-2,2-dimethyl-6-propoxy...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106226(CHEMBL338171 | N-(6-Chloro-3-hydroxy-2,2-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106229(CHEMBL127435 | Ethanesulfonic acid (6-fluoro-3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106223((3S,4R)-Ethanesulfonic acid (6-fluoro-3-hydroxy-2,...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106224(CHEMBL125259 | Ethanesulfonic acid (3-hydroxy-2,2-...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50099567((3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106227((3R,4S)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106230(CHEMBL338273 | Ethanesulfonic acid (6-cyano-3-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Anatomisches Institut der Bayerischen Julius-Maximilians-Universit£t

Curated by ChEMBL
LigandPNGBDBM50033369(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+4nMAssay Description:TP_TRANSPORTER: inhibition of Dopamine uptake (Dopamine: 200 uM) in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82BK9PubMedDrugBank
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50099567((3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 4.45E+4nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
Aventis Pharma Deutschland GmbH

Curated by ChEMBL
LigandPNGBDBM50106225(Butane-1-sulfonic acid (6-cyano-3-hydroxy-2,2-dime...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26H4GPXPubMed