Compile Data Set for Download or QSAR
Found 210 with Last Name = 'graham' and Initial = 'ag'
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012780((3,5-Di-tert-butyl-4-hydroxy-phenyl)-thiophen-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057000(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057004(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056994(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012811(2,6-Di-tert-butyl-4-(2-thiophen-2-yl-vinyl)-phenol...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057004(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012772(2,6-Dimethyl-4-(2-thiophen-3-yl-vinyl)-phenol | CH...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056997(3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057001(CHEMBL361563 | N-[6-(2,3-Difluoro-phenylsulfanyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012778(2,6-Dimethyl-4-(2-thiophen-2-yl-vinyl)-phenol | CH...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070289(2-Benzyl-6-chloro-3-hydroxy-4-(propane-2-sulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056995(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012783(2-Allyl-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056994(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012805(2-Methoxy-6-methyl-4-(2-thiophen-2-yl-vinyl)-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012779(2-Methoxy-6-propyl-4-(2-thiophen-2-yl-vinyl)-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012773(2-Ethyl-6-methoxy-4-(2-thiophen-2-yl-vinyl)-phenol...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029616(5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as the mean percent inhibition of control PGE-2 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070287(2-(4-Fluoro-benzyl)-3-hydroxy-4-(propane-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production; Imax=84%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012768(4-[2-(4-Methoxy-phenyl)-vinyl]-2,6-dimethyl-phenol...)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Selectivity against c-Jun N-terminal kinase 2-alpha 2 protein kinaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070291(6-Chloro-2-(3,4-difluoro-benzyl)-3-hydroxy-4-(prop...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012785(4-[2-(2-Methoxy-phenyl)-vinyl]-2,6-dimethyl-phenol...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000399(CHEMBL292136)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008950(3-(3,5-Di-tert-butyl-4-hydroxy-benzylidene)-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056997(3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012806(4-[2-(4-Fluoro-phenyl)-vinyl]-2,6-dimethyl-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012793(2,6-Dimethyl-4-(2-m-tolyl-vinyl)-phenol | CHEMBL56...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070286(4-Benzenesulfonyl-2-benzyl-3-hydroxy-2H-isoquinoli...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057000(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056998(4-Hydroxy-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012786(4-[2-(4-Chloro-phenyl)-vinyl]-2,6-dimethyl-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057006(3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000360(CHEMBL55680)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012792(2,6-Diisopropyl-4-(2-pyridin-3-yl-vinyl)-phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057005(6-Chloro-3-hydroxy-2-methyl-1-oxo-1,2-dihydro-isoq...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070288(2-(3,4-Difluoro-benzyl)-3-hydroxy-4-(propane-2-sul...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production; Imax=84%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000390(CHEMBL58990)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056996(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012790(4-[2-(2,5-Dimethyl-phenyl)-vinyl]-2,6-dimethyl-phe...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070287(2-(4-Fluoro-benzyl)-3-hydroxy-4-(propane-2-sulfony...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012789(2,6-Di-tert-butyl-4-(2-pyridin-3-yl-vinyl)-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012813(2,6-Dimethyl-4-(2-p-tolyl-vinyl)-phenol | CHEMBL29...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070290(2-Benzyl-3-hydroxy-4-(propane-2-sulfonyl)-2H-isoqu...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50056996(6-Chloro-3-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012794(4-[2-(4-Fluoro-phenyl)-ethyl]-2,6-dimethyl-phenol ...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070290(2-Benzyl-3-hydroxy-4-(propane-2-sulfonyl)-2H-isoqu...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Concentration that caused a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE-2 production.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TQ60PJPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012775(2,6-Dimethyl-4-(2-pyridin-3-yl-vinyl)-phenol | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95857PubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057006(3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2P37PubMed
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