Found 376 with Last Name = 'moore' and Initial = 'ag' 
Affinity DataKi: 1.00E+8nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+8nMAssay Description:Inhibition of 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+8nMAssay Description:Inhibition of histamine H2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+8nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 1nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 2nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
3D Structure (crystal)TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 3nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 4nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 5nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 7nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 8nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 8nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 9nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 10nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 10nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 11nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 12nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 12nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of P2X2 receptorMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 15nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 17nMpH: 7.2 T: 2°CAssay Description:SYK activity is measured by phosphorylation of a peptide substrate (Biotin-EPEGDYEEVLE) with [gamma-33P] ATP. The enzyme reaction was conducted at 20...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 18nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 18nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 23nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 24nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 24nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 24nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 28nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 29nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 29nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 31nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 31nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 31nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 31.6nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 33nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 33nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 35nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 37nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 39.8nMAssay Description:Antagonist activity at rat P2X3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 40nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 43nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
ROCHE PALO ALTO LLC; HOFFMANN-LA ROCHE INC.
US Patent
Affinity DataIC50: 49nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
