Compile Data Set for Download or QSAR
Found 30 with Last Name = 'sutherland' and Initial = 'ag'
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataKi:  3.09E+4nMAssay Description:Non-competitive inhibition of recombinant human MIF assessed as inhibition constant using varying levels of p-hydroxyphenylpyruvate as substrate by L...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM20732((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340241(CHEMBL1760611)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340244(CHEMBL1760614)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340250((6S)-6,15,15,18-tetramethyl-17-oxo-2,3,4,5,6,7,14,...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340248(CHEMBL1760601)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340243(CHEMBL1760613)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340251(CHEMBL1760603)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340247(CHEMBL1760600)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340254(CHEMBL1760606)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340253(CHEMBL1760605)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J3JPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340245(CHEMBL1760598)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J3JPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340242(CHEMBL1760612)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340255(CHEMBL1760607)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 binding to immobilized soluble human CD74 receptor ectodomain...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J3JPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340252(CHEMBL1760604)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340249(CHEMBL1760602)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50547499(CHEMBL4785454)copy SMILES
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21 DE3 binding to recombinant soluble human CD74 receptor ectodomain (73 to 232 r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340240(CHEMBL1760610)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J3JPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50547499(CHEMBL4785454)copy SMILES
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of MIF-induced IL-8 secretion in human foreskin fibroblasts incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340257(CHEMBL1760609)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340256(CHEMBL1760608)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50547499(CHEMBL4785454)copy SMILES
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of recombinant biotinylated human MIF tautomerase activity expressed in Escherichia coli BL21 DE3 assessed as reduction in tautomerization...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50340246(CHEMBL1760599)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of Hsp90alpha after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5VBNPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50547499(CHEMBL4785454)copy SMILES
Affinity DataKd:  6.86E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50458539(CHICAGO SKY BLUE SODIUM | Chicago Sky Blue | Chica...)copy SMILEScopy InChI
Affinity DataKd:  9.04E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8J3JPubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))TBA
LigandPNGBDBM50240404((Ibudilast)1-(2-Isopropyl-pyrazolo[1,5-a]pyridin-3...)copy SMILEScopy InChI
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to recombinant biotinylated human MIF expressed in Escherichia coli BL21 DE3 by surface plasmon resonance assayMore data for this Ligand-Target Pair