Compile Data Set for Download or QSAR
Found 34 with Last Name = 'graff' and Initial = 'ah'
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50463046(CHEMBL1229989)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of human glycolate oxidase expressed in Escherichia coli using glycolate as substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target2-Hydroxyacid oxidase 1(Mus musculus)TBA
LigandPNGBDBM50463047(CHEMBL1794748)copy SMILEScopy InChI
Affinity DataKi:  4.50E+3nMAssay Description:Non competitive inhibition of mouse glycolate oxidase in hyperoxaluric-Agxt knockdown mouse primary hepatocyte assessed as reduction in oxalate produ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572932(CHEMBL4850573)copy SMILES
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572931(CHEMBL4855986)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572933(CHEMBL4861379)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572931(CHEMBL4855986)copy SMILES
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572934(CHEMBL4847068)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572933(CHEMBL4861379)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572930(CHEMBL4873879)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572930(CHEMBL4873879)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572932(CHEMBL4850573)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572934(CHEMBL4847068)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50572929(CHEMBL4864519)copy SMILES
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572929(CHEMBL4864519)copy SMILES
Affinity DataIC50: 0.700nMAssay Description:Inhibition of recombinant mouse LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572931(CHEMBL4855986)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572933(CHEMBL4861379)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572932(CHEMBL4850573)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50103568(CHEMBL3335794)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Competitive inhibition of recombinant human LDHA in the presence of NADH by resazurin dye reduction methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572934(CHEMBL4847068)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572929(CHEMBL4864519)copy SMILES
Affinity DataIC50: 4.70nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572928(CHEMBL4857427)copy SMILES
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)TBA
LigandPNGBDBM50572929(CHEMBL4864519)copy SMILES
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant mouse GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50572930(CHEMBL4873879)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
Target2-Hydroxyacid oxidase 1(Mus musculus)TBA
LigandPNGBDBM50572928(CHEMBL4857427)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant mouse GOX expressed in Escherichia coli C41 (DE3) using glycolate as substrate preincubated for 10 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
TargetHydroxyacid oxidase 1(Sus scrofa)TBA
LigandPNGBDBM50572935(CHEMBL4848350)copy SMILES
Affinity DataIC50: 87nMAssay Description:Inhibition of pig HAO1 in presence of NADH by spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572929(CHEMBL4864519)copy SMILES
Affinity DataIC50: 136nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572931(CHEMBL4855986)copy SMILES
Affinity DataIC50: 143nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572934(CHEMBL4847068)copy SMILES
Affinity DataIC50: 170nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572932(CHEMBL4850573)copy SMILES
Affinity DataIC50: 198nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572933(CHEMBL4861379)copy SMILES
Affinity DataIC50: 230nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))TBA
LigandPNGBDBM86137(LDHA Inhibitor, 33)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human LDHA expressed in BL21 gold (DE3) using sodium pyruvate as substrate preincubated for 10 mins followed by sodium pyru...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))TBA
LigandPNGBDBM50572930(CHEMBL4873879)copy SMILES
Affinity DataIC50: 732nMAssay Description:Inhibition of LDHA in wild type CD1 mouse primary hepatocyte assessed as inhibition of lactate production using pyruvate as substrate measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V128MVPubMed