Compile Data Set for Download or QSAR
Found 76 with Last Name = 'vovk' and Initial = 'ai'
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253763(CHEMBL4067565)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-inhibitor complex using varying levels of xanthine as substrate by Line-weav...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Competitive inhibition of recombinant human PTP1B expressed in Escherichia coli using varying levels of p-nitrophenol as substrate by Lineweaver-burk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253763(CHEMBL4067565)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253764(CHEMBL4078467)copy SMILEScopy InChI
Affinity DataKi:  128nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-inhibitor complex using varying levels of xanthine as substrate by Line-weav...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Competitive inhibition of recombinant human PTP1B expressed in Escherichia coli using varying levels of p-nitrophenol as substrate by Lineweaver-burk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)copy SMILEScopy InChI
Affinity DataKi:  680nMAssay Description:Reversible inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)copy SMILEScopy InChI
Affinity DataKi:  740nMAssay Description:Reversible inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)copy SMILEScopy InChI
Affinity DataKi:  980nMAssay Description:Competitive inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol by Lineweave...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253764(CHEMBL4078467)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272706((+/-)-rac-alpha-(N-benzylamino)benzylphosphonic ac...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272707((R)-N-benzyl(phenyl)(phosphono)methanaminium chlor...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272138((R)-N-((S)-(4-methoxyphenyl)(phosphono)methyl)-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272136((R)-1-phenyl-N-((S)-phenyl(phosphono)methyl)ethana...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253764(CHEMBL4078467)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of bovine milk xanthine-oxidase using xanthine as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253766(CHEMBL4102721)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253837(CHEMBL4086326)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253840(CHEMBL4066914)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253765(CHEMBL4064851)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253838(CHEMBL4094987)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306213(CHEMBL611318 | {[25,26,27,28-tetrahydroxy-11,17,23...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant PTPbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74QMPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253799(CHEMBL4097460)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272708((S)-N-benzyl(phenyl)(phosphono)methanaminium chlor...)copy SMILEScopy InChI
Affinity DataIC50: 198nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TCPTP catalytic domain (2 to 315 residues) expressed in Escherichia coli using p-nitrophenol as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272137((S)-N-((R)-(4-methoxyphenyl)(phosphono)methyl)-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetProstatic acid phosphatase(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50272135((S)-1-phenyl-N-((R)-phenyl(phosphono)methyl)ethana...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of human prostatic acid phosphataseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X3MPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253800(CHEMBL4093490)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253763(CHEMBL4067565)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of bovine milk xanthine-oxidase using xanthine as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253839(CHEMBL4079426)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253798(CHEMBL4105165)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531903(CHEMBL4530344)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant full length PTP1B (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531903(CHEMBL4530344)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50580((2Z)-2-(3,4-dihydroxybenzylidene)-6-hydroxy-coumar...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of SHP2 (unknown origin) assessed as p-nitrophenyl phosphate conversion to p-nitrophenol after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441102(CHEMBL611611)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306212(CHEMBL592901 | {[25,26,27,28-tetrahydroxy-11,17,23...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant PTPbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB74QMPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50253767(CHEMBL4087307)copy SMILEScopy InChI
Affinity DataIC50: 3.84E+3nMAssay Description:Mixed-type inhibition of bovine milk xanthine oxidase assessed as enzyme-substrate-inhibitor complex using varying levels of xanthine as substrate by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3V3NPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50306211(CHEMBL611317 | {[17-(diphosphonomethyl)-26,28-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50441103(CHEMBL2430577)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant truncated PTP1B (unknown origin) using pTyr1146 as substrate assessed as inorganic phosphate level after 20 mins by spectro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z96BFPubMed
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