Compile Data Set for Download or QSAR
Found 182 with Last Name = 'main' and Initial = 'aj'
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036427(CHEMBL350265 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036401(CHEMBL163221 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036399(Axitirome | CHEMBL159682 | N-(4-{3-[(4-Fluoro-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 0.150nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036402(CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036418(CHEMBL350049 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036423(CHEMBL164421 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036411(CHEMBL163324 | N-{3,5-Dichloro-4-[3-(4-chloro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.270nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036410(CHEMBL159976 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036424(CHEMBL159334 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036408(CHEMBL161828 | N-{4-[3-(4-Chloro-benzyl)-4-hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036404(CHEMBL159595 | N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036395(CHEMBL350199 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036420(CHEMBL161535 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036406(CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036397(CHEMBL348983 | N-[3,5-Dichloro-4-(4-hydroxy-3-isop...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036405(CHEMBL434476 | N-(3,5-Dichloro-4-{3-[(4-chloro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036398(CHEMBL162692 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50003776(8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CVBPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036426(CHEMBL159610 | N-{4-[3-(4-Fluoro-benzoyl)-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036415(CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036414(CHEMBL346112 | N-{4-[3-(4-Chloro-benzoyl)-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036430(CHEMBL347713 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036422(CHEMBL163020 | N-[3,5-Difluoro-4-(4-hydroxy-3-isop...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50003777(8-(4-Chloro-benzenesulfonylamino)-2-(5-pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CVBPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036409((S)-2-Amino-3-[3,5-dibromo-4-(4-hydroxy-3-isopropy...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036396(CHEMBL163320 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50280267(CHEMBL295121 | [3-[3-(4-Chloro-benzenesulfonylamin...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36QQ
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50300929((S)-2-amino-3-(4-(4-amino-6-(biphenyl-2-ylmethylam...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SV0PubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036432(CHEMBL264041 | N-[4-(3-Isopropyl-phenoxy)-3,5-dime...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50280268(3-[3-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36QQ
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036403(CHEMBL352126 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50243565((S)-2-amino-3-(4-(5-(naphthalen-2-ylmethylamino)py...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FZMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50300932((S)-2-amino-3-(4-(4-amino-6-((4'-methylbiphenyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SV0PubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036412(CHEMBL161245 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50003779(8-(4-Chloro-benzenesulfonylamino)-6-pyridin-3-ylme...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CVBPubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50280264(3-[5-[2-(4-Chloro-benzenesulfonylamino)-ethyl]-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory concentration of the compound against thromboxane synthase enzyme from human microsomal platelet preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36QQ
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291519(3-(3-Biphenyl-4-yl-but-2-enoylamino)-4-methoxy-ben...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RW3
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291521((E)-3-Biphenyl-4-yl-N-[2-methoxy-5-(1H-tetrazol-5-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro binding affinity towards LTB4 receptor determined by measuring the displacement of [3H]-LTB4 from isolated neutrophilsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8RW3
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50300935((S)-3-{4-[4-(1-Adamantan-1-yl-ethylamino)-6-amino-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SV0PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
CIBA-GEIGY Corporation

Curated by ChEMBL
LigandPNGBDBM50003773(8-(4-Chloro-benzenesulfonylamino)-5-(2-pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The compound was tested in vitro for its inhibitory activity against thromboxane synthase A2 (TXA2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8CVBPubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036407(CHEMBL441101 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T43TRCPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50243613((S)-2-Amino-3-(4-(4-amino-6-((naphthalene-2-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SV0PubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50243613((S)-2-Amino-3-(4-(4-amino-6-((naphthalene-2-ylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FZMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of TPH1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0FZMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))
Princ

Curated by ChEMBL
LigandPNGBDBM50300934((2S)-2-amino-3-(4-(4-amino-6-(1-(biphenyl-4-yl)eth...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant TPH1 by continuous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SV0PubMed
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