Affinity DataIC50: 0.25nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Tested for binding activity against [3H]-LTB4 to whole human neutrophil with halh maximal inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Tested for antagonistic activity against LTB4 receptor in guinea pig spleen membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 30.3nMAssay Description:Tested for antagonistic activity in mouse spleen membrane against LTB4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 171nMAssay Description:Inhibition of VCAM binding to Alpha4-beta1 integrin of human eosinophil cellMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 347nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 495nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of Alpha4-beta1 integrin in Jurkat cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant sVCAM-1 binding to alpha4-beta1 integrin (VLA-4) in ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPKAPK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cdk2More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK2/ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Pfizer Global Researchand Development
Curated by ChEMBL
Pfizer Global Researchand Development
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1/SAPK1cMore data for this Ligand-Target Pair
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