Found 66 with Last Name = 'o''neill' and Initial = 'aj' 
Affinity DataIC50: 13nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibition of Escherichia coli LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei LeuRS assessed as reduction in protein synthesis pretreated for 20 mins in presence of [14C]Leu followed by ATP addi...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human LeuRS assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human cytoplasmic LeuRS assessed as reduction in protein synthesis measured after 10 mins in presence of [3H]Leu by scintillation count...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Staphylococcus aureus (strain NCTC 8325))
Oxford Drug Design Ltd.
Curated by ChEMBL
Oxford Drug Design Ltd.
Curated by ChEMBL
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of Staphylococcus aureus LeuRS expressed in Escherichia coli M15 cells assessed as reduction in ATP consumptionMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.19E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.26E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae)
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assayMore data for this Ligand-Target Pair
