Compile Data Set for Download or QSAR
Found 20 with Last Name = 'hatzopoulos' and Initial = 'ak'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 25.1nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 26.7nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)copy SMILEScopy InChI
Affinity DataIC50: 40.7nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36355(4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 42.8nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36354(4-(6-(4-isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 148nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)copy SMILEScopy InChI
Affinity DataIC50: 215nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 235nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 318nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36355(4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 527nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)copy SMILEScopy InChI
Affinity DataIC50: 565nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 999nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM160333(US9040694, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36355(4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.58E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM36355(4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin...)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 2.92E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X065SNUS Patent