Compile Data Set for Download or QSAR
Found 242 with Last Name = 'bridges' and Initial = 'am'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50091438((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Binding affinity of the compound at C-C chemokine receptor type 2 was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4V42PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4V42PubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504166(CHEMBL4529901)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Displacement of biotinylated H4 peptide from His6/FLAG-tagged TEV fused ATAD2 bromodomain (950 to 1148 residues) (unknown origin) expressed in Escher...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4V42PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50133111(6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibitory activity of the compound against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4V42PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096314(CHEMBL3586722)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504159(CHEMBL4583297)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetATPase family AAA domain-containing protein 2B(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504159(CHEMBL4583297)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Displacement of biotinylated H4 peptide from ATAD2B bromodomain (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504158(CHEMBL4522533)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Displacement of Alexa Fluor 488 labelled ligand from ATAD2 bromodomain (981 to 1121 residues) (unknown origin) expressed in Escherichia coli BL21(DE3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096320(CHEMBL3586721)copy SMILEScopy InChI
Affinity DataIC50: 631nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096317(CHEMBL3586724)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096281(CHEMBL3585460)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096280(CHEMBL3585459)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096318(CHEMBL3586719)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096299(CHEMBL3585451)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096321(CHEMBL3586720)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504137(CHEMBL4473637)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504151(CHEMBL4519291)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504137(CHEMBL4473637)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504137(CHEMBL4473637)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096313(CHEMBL3585449)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096312(CHEMBL3586723)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096314(CHEMBL3586722)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096308(CHEMBL3585461)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096282(CHEMBL3585455)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096302(CHEMBL3585454)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096301(CHEMBL3585453)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096282(CHEMBL3585455)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096296(CHEMBL3585457)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096281(CHEMBL3585460)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096308(CHEMBL3585461)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096298(CHEMBL3585458)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096312(CHEMBL3586723)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096283(CHEMBL3585456)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096280(CHEMBL3585459)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096320(CHEMBL3586721)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetChromatin remodeling regulator CECR2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504159(CHEMBL4583297)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of CECR2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504140(CHEMBL4444016)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGAKRHRKV-biotin) from His6/FLAG-tagged TEV fused ATAD2 bromodomain (981 to 1121 residues) (unknown ori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096315(CHEMBL3586725)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50093460(CHEMBL3586713)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096311(CHEMBL3586717)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096317(CHEMBL3586724)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096321(CHEMBL3586720)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096301(CHEMBL3585453)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50096309(CHEMBL3586716)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Displacement of I-BET762 from 6His-Thr-BRD4 (1 to 477) BD1 (unknown origin) harboring BD2 Y390A mutant after 30 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of ATAD2 in human PBMC assessed as inhibition of LPS-stimulated IL-6 release after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50096307(CHEMBL3585462)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7XQNPubMed
TargetTranscription initiation factor TFIID subunit 1(Homo sapiens (Human))
Cellzome

Curated by ChEMBL
LigandPNGBDBM50504159(CHEMBL4583297)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of TAF1 BD2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3VZVPubMed
Displayed 1 to 50 (of 242 total ) | Next | Last >>
Jump to: