TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor (unknown origin) in cerebral cortex membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 0.990nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor (unknown origin) in cerebral cortex membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5HT1A receptor (unknown origin) expressed in HEK293 cells membranes incubated for 60 mins by scintillation counti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 195nMAssay Description:Inhibition of serotonin reuptake in SERT (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHO cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 0.820nMAssay Description:Antagonist activity at 5HT7R receptor (unknown origin) assessed as forskolin-mediated cAMP accumulation preincubated for 30 mins followed by forskoli...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 0.920nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
China State Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of rat synaptosomes 5HT transporter assessed as reduction in [3H]serotonin reuptake incubated for 15 mins by scintillation counting methodMore data for this Ligand-Target Pair
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