Compile Data Set for Download or QSAR
Found 110 with Last Name = 'beccari' and Initial = 'ar'
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM419120(acs.jmedchem.1c00409_ST.487 | cmdc.202100576, 8d(N...)copy SMILEScopy InChI
Affinity DataKi:  9.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RJDPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM228619(US9345789, Z-DEVD-FMK)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM228619(US9345789, Z-DEVD-FMK)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM46060(2-(2,5-dimethylphenyl)-6-fluoranyl-1,2-benzothiazo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314133(CHEMBL1093713 | N-(3,5-Dimethylphenyl)-N'-hydroxyo...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM46060(2-(2,5-dimethylphenyl)-6-fluoranyl-1,2-benzothiazo...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314134(CHEMBL1093041 | N-(3-Ethylphenyl)-N'-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314135(CHEMBL1093359 | N-(3,4-Dimethylphenyl)-N'-hydroxyo...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314133(CHEMBL1093713 | N-(3,5-Dimethylphenyl)-N'-hydroxyo...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314134(CHEMBL1093041 | N-(3-Ethylphenyl)-N'-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM442806(Bonaphthone)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314135(CHEMBL1093359 | N-(3,4-Dimethylphenyl)-N'-hydroxyo...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314136(CHEMBL1089339 | N-Hydroxy-N'-(3-methylphenyl)octan...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314136(CHEMBL1089339 | N-Hydroxy-N'-(3-methylphenyl)octan...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314137(CHEMBL1091487 | N-Hydroxy-N'-(4-methoxyphenyl)octa...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314138(CHEMBL1092762 | N-Hydroxy-N'-(4-methylphenyl)octan...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | US20230414581, Co...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM442805(Felbinac ethyl)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM442806(Bonaphthone)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50418081(OLTIPRAZ)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314138(CHEMBL1092762 | N-Hydroxy-N'-(4-methylphenyl)octan...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314137(CHEMBL1091487 | N-Hydroxy-N'-(4-methoxyphenyl)octa...)copy SMILEScopy InChI
Affinity DataIC50: 137nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 147nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMedDrugBank
TargetHistone deacetylase 1(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314139(CHEMBL1093042 | N-(4-Ethylphenyl)-N'-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Ex vivo inhibition of human HDAC1 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM64748(7-[(4-methyl-1-piperazinyl)-[4-(trifluoromethyl)ph...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM442805(Felbinac ethyl)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50418081(OLTIPRAZ)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50058655(1,1',1'',1'''-[disulfanediylbis(carbonothioylnitri...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 240nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RJDPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
UMR CNRS 6026-Universit£ Rennes 1

Curated by ChEMBL
LigandPNGBDBM50314139(CHEMBL1093042 | N-(4-Ethylphenyl)-N'-hydroxyoctane...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Ex vivo inhibition of human HDAC3 in human Caco2 cells by flurometric cellular activity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7HFBPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50197301(CHEMBL3922662 | ebselen derivative 1d)copy SMILEScopy InChI
Affinity DataIC50: 240nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RJDPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50197300(CHEMBL3912164 | ebselen derivative 2e)copy SMILEScopy InChI
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RJDPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50197349(CHEMBL3983492 | ebselen derivative 1e)copy SMILEScopy InChI
Affinity DataIC50: 260nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445RJDPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)TBA
LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
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