Compile Data Set for Download or QSAR
Found 116 with Last Name = 'brown' and Initial = 'ar'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataKi:  2.51nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataKi:  25.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)copy SMILEScopy InChI
Affinity DataKi:  31.6nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)copy SMILEScopy InChI
Affinity DataKi:  34.7nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)copy SMILEScopy InChI
Affinity DataKi:  37.1nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)copy SMILEScopy InChI
Affinity DataKi:  63.1nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of ROCK-1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417674(CHEMBL1643361)copy SMILEScopy InChI
Affinity DataKi:  3.16E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)copy SMILEScopy InChI
Affinity DataKi:  7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417668(CHEMBL1643368)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)copy SMILEScopy InChI
Affinity DataKi:  2.51E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataKi:  7.94E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417851(CHEMBL1667977)copy SMILEScopy InChI
Affinity DataIC50: 31.6nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 38.9nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417853(CHEMBL1667975)copy SMILEScopy InChI
Affinity DataIC50: 47.9nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417847(CHEMBL1667970)copy SMILEScopy InChI
Affinity DataIC50: 57.5nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 61.7nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417858(CHEMBL1667966)copy SMILEScopy InChI
Affinity DataIC50: 72.4nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)copy SMILEScopy InChI
Affinity DataIC50: 79.4nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetcAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human PrkX by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417849(CHEMBL1667979)copy SMILEScopy InChI
Affinity DataIC50: 81.3nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 91.2nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417850(CHEMBL1667978)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417848(CHEMBL1667980)copy SMILEScopy InChI
Affinity DataIC50: 166nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417857(CHEMBL1667969)copy SMILEScopy InChI
Affinity DataIC50: 186nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417852(CHEMBL1667976)copy SMILEScopy InChI
Affinity DataIC50: 229nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417683(CHEMBL1643573)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataIC50: 245nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of ROCK1 by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Inhibition of human PKCdelta by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417847(CHEMBL1667970)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417842(CHEMBL1667965)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 398nMAssay Description:Inhibition of human PKCeta by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417687(CHEMBL1643356)copy SMILEScopy InChI
Affinity DataIC50: 427nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 501nMAssay Description:Inhibition of human PKCmu by RFBA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417856(CHEMBL1667972)copy SMILEScopy InChI
Affinity DataIC50: 525nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)copy SMILEScopy InChI
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK-2 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417678(CHEMBL1643365)copy SMILEScopy InChI
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)copy SMILEScopy InChI
Affinity DataIC50: 575nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417854(CHEMBL1667974)copy SMILEScopy InChI
Affinity DataIC50: 589nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417670(CHEMBL1643357)copy SMILEScopy InChI
Affinity DataIC50: 589nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417843(CHEMBL1667967)copy SMILEScopy InChI
Affinity DataIC50: 661nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417846(CHEMBL1667968)copy SMILEScopy InChI
Affinity DataIC50: 676nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM14031(5-(1,4-diazepane-1-sulfonyl)-1,2-dihydroisoquinoli...)copy SMILEScopy InChI
Affinity DataIC50: 759nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417844(CHEMBL1667963)copy SMILEScopy InChI
Affinity DataIC50: 759nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
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