Compile Data Set for Download or QSAR
Found 182 with Last Name = 'ougolkov' and Initial = 'av'
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267760(3-Benzofuran-3-yl-4-(7-methoxymethyl-1-methyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267461(3-(5-Fluoro-1-methyl-1H-indol-3-yl)-4-(6-hydroxyme...)copy SMILEScopy InChI
Affinity DataIC50: 0.350nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of CHK1More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267607(3-(5-Bromo-1-methyl-1H-indol-3-yl)-4-(6-hydroxymet...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.640nMAssay Description:Inhibition of AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267800(3-(6-Hydroxymethylbenzofuran-3-yl)-4-(7-methoxymet...)copy SMILEScopy InChI
Affinity DataIC50: 0.730nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267523(3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312620(CHEMBL1094708 | Octanedioic Acid-{3-[1-(3-Aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.01nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267802(3-[3-(4-Benzofuran-3-yl-2,5-dioxo-2,5-dihydro-1H-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312621(CHEMBL1091815 | Octanedioic Acid-{3-[1-(3,5-Difluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312620(CHEMBL1094708 | Octanedioic Acid-{3-[1-(3-Aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 1.55nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312622(CHEMBL1088735 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 1.66nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312621(CHEMBL1091815 | Octanedioic Acid-{3-[1-(3,5-Difluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312629(CHEMBL1088736 | Octanedioic Acid-{3-[1-(3,5-Bis(hy...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312624(CHEMBL1091475 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312620(CHEMBL1094708 | Octanedioic Acid-{3-[1-(3-Aminophe...)copy SMILEScopy InChI
Affinity DataIC50: 2.52nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312628(CHEMBL1094709 | Octanedioic Acid Hydroxyamide-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312626(CHEMBL1088734 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312624(CHEMBL1091475 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312622(CHEMBL1088735 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 3.04nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312628(CHEMBL1094709 | Octanedioic Acid Hydroxyamide-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CDK9/cyclin T1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312629(CHEMBL1088736 | Octanedioic Acid-{3-[1-(3,5-Bis(hy...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(CHEMBL1076939 | Octanedioic Acid-{3-[1-(3-Fluoro-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.39nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312626(CHEMBL1088734 | Octanedioic Acid Hydroxyamide-{3-[...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267520(3-(5-Fluoro-1-methyl-1H-indol-3-yl)-4-(6-hydroxybe...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312627(CHEMBL1094707 | Octanedioic Acid-[3-(1-Cyclohexyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CDK5/P35More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(CHEMBL1076939 | Octanedioic Acid-{3-[1-(3-Fluoro-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.85nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312630(CHEMBL1094710 | Octanedioic Acid-[3-(4-Cyclohexyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312628(CHEMBL1094709 | Octanedioic Acid Hydroxyamide-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312623(CHEMBL1076939 | Octanedioic Acid-{3-[1-(3-Fluoro-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.06nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267759(3-(6-Hydroxymethylbenzofuran-3-yl)-4-(7-hydroxymet...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312621(CHEMBL1091815 | Octanedioic Acid-{3-[1-(3,5-Difluo...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312630(CHEMBL1094710 | Octanedioic Acid-[3-(4-Cyclohexyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of HDAC3 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267758(3-Benzofuran-3-yl-4-(7-hydroxymethyl-1-methyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312629(CHEMBL1088736 | Octanedioic Acid-{3-[1-(3,5-Bis(hy...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of HDAC1 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312629(CHEMBL1088736 | Octanedioic Acid-{3-[1-(3,5-Bis(hy...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50312628(CHEMBL1094709 | Octanedioic Acid Hydroxyamide-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R52PubMed
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50267605(3-(benzofuran-3-yl)-4-(5-bromo-1-methyl-1H-indol-3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
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