Compile Data Set for Download or QSAR
Found 591 with Last Name = 'ellinger' and Initial = 'b'
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50278487(CHEMBL3585376)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of 125-I echistatin from Vitronectin receptor (alpha v beta3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50B3PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50278488(CHEMBL4159241)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione disulfide as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50B3PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50278486(CHEMBL4160100)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMAssay Description:Mixed-type inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione d...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50B3PubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551183(CHEMBL4747846)copy SMILES
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothione disulfide as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50B3PubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551184(CHEMBL4797185)copy SMILES
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551180(CHEMBL4760251)copy SMILES
Affinity DataKi:  1.48E+4nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551177(CHEMBL4762279)copy SMILES
Affinity DataKi:  1.53E+4nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551178(CHEMBL4785591)copy SMILES
Affinity DataKi:  1.92E+4nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50278489(CHEMBL4170316)copy SMILEScopy InChI
Affinity DataKi:  2.24E+4nMAssay Description:Non-competitive inhibition of Trypanosoma cruzi trypanothione reductase assessed as reduction in NADPH consumption using varying levels of trypanothi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD50B3PubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551181(CHEMBL54725)copy SMILES
Affinity DataKi:  3.72E+4nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50386758(CHEMBL2046893)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551182(CHEMBL4754292)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551179(CHEMBL4778279)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551175(CHEMBL1993081)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551174(CHEMBL158919)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551173(CHEMBL4753331)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50062821(6-Benzyloxy-pyrimidine-2,4-diamine | CHEMBL121445)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50551176(CHEMBL4748094)copy SMILES
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47SSHPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600683(CHEMBL5184936)copy SMILES
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600703(CHEMBL5201183)copy SMILES
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600694(CHEMBL5204239)copy SMILES
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600702(CHEMBL5199171)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600693(CHEMBL5175012)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600684(CHEMBL5182125)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600701(CHEMBL5200612)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600679(CHEMBL426 | Methotrexate | TCMDC-123832 | TCMDC-12...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM228619(US9345789, Z-DEVD-FMK)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM228619(US9345789, Z-DEVD-FMK)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM46060(2-(2,5-dimethylphenyl)-6-fluoranyl-1,2-benzothiazo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50050426(6-(Naphthalen-1-ylaminomethyl)-pteridine-2,4-diami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600700(CHEMBL5188304)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600692(CHEMBL5197107)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600689(CHEMBL5175397)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600688(CHEMBL5198855)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50050426(6-(Naphthalen-1-ylaminomethyl)-pteridine-2,4-diami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50600683(CHEMBL5184936)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM46060(2-(2,5-dimethylphenyl)-6-fluoranyl-1,2-benzothiazo...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
LigandPNGBDBM50600679(CHEMBL426 | Methotrexate | TCMDC-123832 | TCMDC-12...)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600685(CHEMBL5171609)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetDihydrofolate reductase(Homo sapiens (Human))TBA
LigandPNGBDBM50600679(CHEMBL426 | Methotrexate | TCMDC-123832 | TCMDC-12...)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600691(CHEMBL5205559)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50600694(CHEMBL5204239)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase 1(Leishmania major)TBA
LigandPNGBDBM50600693(CHEMBL5175012)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM442806(Bonaphthone)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600682(CHEMBL5193564)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600690(CHEMBL5206994)copy SMILES
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
TargetPteridine reductase, putative(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))TBA
LigandPNGBDBM50600679(CHEMBL426 | Methotrexate | TCMDC-123832 | TCMDC-12...)copy SMILES
Affinity DataIC50: 50nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8JJCPubMed
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