Compile Data Set for Download or QSAR
Found 43 with Last Name = 'hibner' and Initial = 'b'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139601(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(met...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMedDrugBank
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139618(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139621(4-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139626(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139620(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139597(4-(4-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139623(4-{4-[3-(4-Bromo-3-trifluoromethyl-phenyl)-ureido]...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139627(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(4-(5-(m...)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139602(5-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139598(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139635(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139596(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139628(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139606(CHEMBL168049 | N-(2-Dimethylamino-ethyl)-5-{4-[3-(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139611(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139629(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139609(3-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139605(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139636(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139617(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139612(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139599(5-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139613(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139608(CHEMBL164827 | N-(6-Methoxy-pyridin-3-yl)-3-{4-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139622(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139630(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139624(1-(4-bromo-3-(trifluoromethyl)phenyl)-3-(4-(2-(dim...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139625(3-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139604(1-(5-tert-Butyl-isoxazol-3-yl)-3-[4-(pyridin-4-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139607(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139632(3-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139610(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139631(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139619(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139600(CHEMBL164015 | N-(4-Dimethylamino-phenyl)-3-{4-[3-...)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139603(CHEMBL164029 | N-Benzyl-3-{4-[3-(5-tert-butyl-isox...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139633(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139615(4-{4-[3-(2-Methoxy-5-trifluoromethyl-phenyl)-ureid...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50105619(1-(5-tert-Butyl-isoxazol-3-yl)-3-(4-phenoxy-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139634(4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50139616(3-{4-[3-(5-tert-Butyl-isoxazol-3-yl)-ureido]-pheno...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TM79JTPubMed