Compile Data Set for Download or QSAR
Found 257 with Last Name = 'janssen' and Initial = 'b'
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605601(CHEMBL5184138)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605598(CHEMBL5188193)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605597(CHEMBL5204161)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264866(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CTHPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605555(CHEMBL5173250)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605593(CHEMBL5179642)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM210802(US10463663, Example 40 | US11129828, Example 40 | ...)copy SMILEScopy InChI
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605599(CHEMBL5178413)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM28043(7-amino-4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5M4PPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273805(CHEMBL4127623)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273870(CHEMBL4126247)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605592(CHEMBL5179643)copy SMILES
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273886(CHEMBL4129012)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273809(CHEMBL4127804)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605589(CHEMBL5196542)copy SMILES
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273869(CHEMBL4127964)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605595(CHEMBL5174518)copy SMILES
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273831(CHEMBL4128143)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605552(CHEMBL5204839)copy SMILES
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273900(CHEMBL4128261)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273872(CHEMBL4129575)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273901(CHEMBL4129431)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273843(CHEMBL4126768)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264865((4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CTHPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273846(CHEMBL4126984)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273871(CHEMBL4126126)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605575(CHEMBL5180296)copy SMILES
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273797(CHEMBL4126304)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605586(CHEMBL5184060)copy SMILES
Affinity DataIC50: 46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM28037(4-(3-phenylphenyl)thieno[2,3-c]pyridine-2-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5M4PPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273798(CHEMBL4129046)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50264773(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CTHPubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273807(CHEMBL4127608)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605600(CHEMBL5179598)copy SMILES
Affinity DataIC50: 51nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human FASN KR-domain after 20 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605585(CHEMBL5208196)copy SMILES
Affinity DataIC50: 54nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273892(CHEMBL4127027)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605576(CHEMBL5188286)copy SMILES
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605577(CHEMBL5191702)copy SMILES
Affinity DataIC50: 72nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273836(CHEMBL4129242)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM28039(5-[4-(3-phenylphenyl)thieno[2,3-c]pyridin-2-yl]-1H...)copy SMILEScopy InChI
Affinity DataIC50: 80nMpH: 7.5 T: 2°CAssay Description:The COT direct HTRF assay was carried out using biotin-MEK1 as a substrate. The reaction was carried out in black 96 half-well plates. At designated...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5M4PPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605581(CHEMBL5183719)copy SMILES
Affinity DataIC50: 80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605579(CHEMBL5179752)copy SMILES
Affinity DataIC50: 82nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Research and Development LLC

Curated by ChEMBL
LigandPNGBDBM50273890(CHEMBL4129240)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB55FWPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605588(CHEMBL5201918)copy SMILES
Affinity DataIC50: 87nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605578(CHEMBL5192292)copy SMILES
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50265350(4-(4'-chlorobiphenyl-4-yloxy)-2-(2H-tetrazol-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant COT by HTRF-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3CTHPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50605571(CHEMBL5173262)copy SMILES
Affinity DataIC50: 91nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MG7TK7PubMed
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