Compile Data Set for Download or QSAR
Found 422 with Last Name = 'twenter' and Initial = 'b'
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220118(US9271961, EM1404)copy SMILEScopy InChI
Affinity DataKi:  6.90nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  380nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  1.32E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)copy SMILEScopy InChI
Affinity DataKi:  2.66E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  8.20E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220121(US9271961, Cloxazolam)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  2.10E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220116(US9271961, CBM)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)copy SMILEScopy InChI
Affinity DataKi:  1.06E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of COX2 expressed in baculovirus infected SF-21 cells assessed as formation of PGH2 from PGG2 using arachidonic acid as substrate preincub...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant COX2More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant AKR1B1 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385687(CHEMBL2041555)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385719(CHEMBL2043307)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FD4PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337281(3-[N-(4-nitrophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220122(US9271961, BMT 3-224)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM35916(flufenamic acid analogue, 42)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385688(CHEMBL2041556)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220124(US9271961, BMT 4-90)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385710(CHEMBL2043300)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385686(CHEMBL2041554)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385689(CHEMBL2041557)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337282(3-[N-(4-acetylphenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337282(3-[N-(4-acetylphenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FD4PubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337282(3-[N-(4-acetylphenyl)amino]benzoic acid | CHEMBL16...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385722(CHEMBL2043310)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337283(3-[N-(4-trifluoromethylphenyl)amino]benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385716(CHEMBL2043303)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50382163(CHEMBL2023820)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant AKR1C3 assessed as enzyme catalyzed oxidation of S-tetralol by fluorimetric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385771(CHEMBL2040884)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50385761(CHEMBL2043313)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM220115(US9271961, 13)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM69369(2-(4-methoxyanilino)benzoic acid | 2-(p-anisidino)...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24XGPPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
The Trustees of the University of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B22US Patent
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