Compile Data Set for Download or QSAR
Found 240 with Last Name = 'votta' and Initial = 'b'
LigandPNGBDBM50574936(CHEMBL4857880)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50574935(CHEMBL4866182)copy SMILES
Affinity DataIC50: 0.158nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50467989(CHEMBL4282034)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50574921(CHEMBL4856422)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of rat RIPK2 preincubated for 10 mins followed by addition of fluorescent-labeled 2-Methyl-5-(2-propen-l-yloxy)aniline measured after 10 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human full-length FLAG/His-tagged RIP2 measured after 2 hrs by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of fluorescent-labelled ligand binding to rat RIP2K preincubated for 10 mins followed by fluorescent-labelled ligand addition and measured...More data for this Ligand-Target Pair
LigandPNGBDBM50467979(CHEMBL4285837)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50467986(CHEMBL4289904)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50467980(CHEMBL4292228)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells assessed as reduction in MDP-induced IL8 production measured after 22 hrs by HTRF fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XKFPubMed
LigandPNGBDBM50516676(CHEMBL4473105)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of fluorescent-labelled ligand binding to human RIP2K preincubated for 10 mins followed by fluorescent-labelled ligand addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XKFPubMed
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))TBA
LigandPNGBDBM50574939(CHEMBL4870089)copy SMILES
Affinity DataIC50: 5nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50574922(CHEMBL4872212)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescent-labelled ligand binding to human RIP2K preincubated for 10 mins followed by fluorescent-labelled ligand addition and measur...More data for this Ligand-Target Pair
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50467980(CHEMBL4292228)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50467988(CHEMBL4285462)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50128684(CHEMBL3628627)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full-length FLAG-6His-TEV tagged human RIP2 expressed in Sf9 cells assessed as reduction in autophosphorylation pre-incubated for 30 mi...More data for this Ligand-Target Pair
LigandPNGBDBM50574941(CHEMBL4848861)copy SMILES
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50184479(CHEMBL3822791)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50467982(CHEMBL4281602)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50574929(CHEMBL4864469)copy SMILES
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50128684(CHEMBL3628627)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full-length FLAG-6His-TEV tagged human RIP2 expressed in Sf9 cells by fluorescent polarization assayMore data for this Ligand-Target Pair
LigandPNGBDBM50574939(CHEMBL4870089)copy SMILES
Affinity DataIC50: 7.90nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))TBA
LigandPNGBDBM50574934(CHEMBL4876228)copy SMILES
Affinity DataIC50: 7.90nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50184727(CHEMBL3822938)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50574937(CHEMBL4863259)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50045333(CHEBI:90705 | SB-203580)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length FLAG-6His-TEV tagged human RIP2 expressed in Sf9 cells assessed as reduction in autophosphorylation pre-incubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5VTMPubMed
LigandPNGBDBM25195(4-methyl-3-{[6-(pyridin-3-yl)quinolin-4-yl]amino}p...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50184764(CHEMBL3822577)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50574920(CHEMBL4863839)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50574925(CHEMBL4860212)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50574932(CHEMBL4866917)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
LigandPNGBDBM50128687(CHEMBL3628628)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of full-length FLAG-6His-TEV tagged human RIP2 expressed in Sf9 cells assessed as reduction in autophosphorylation pre-incubated for 30 mi...More data for this Ligand-Target Pair
TargetNucleotide-binding oligomerization domain-containing protein 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of NOD2 in human monocytes assessed as reduction in MDP-induced TNFalpha production preincubated for 30 mins followed by MDP-stimulation a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XKFPubMed
LigandPNGBDBM50574940(CHEMBL4845683)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of RIPK2 in rat whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))TBA
LigandPNGBDBM50574939(CHEMBL4870089)copy SMILES
Affinity DataIC50: 13nMAssay Description:Binding affinity to human His-thr XIAP BIR3 (241 to 356) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50574934(CHEMBL4876228)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD739FPubMed
LigandPNGBDBM50467986(CHEMBL4289904)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of RIPK3 (unknown origin) preincubated for 10 mins followed by addition of fluorescent-labeled 2-Methyl-5-(2-propen-l-yloxy)aniline measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50184765(CHEMBL3823499)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM50184725(CHEMBL3824056)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Competitive inhibition of full length FLAG-His-tagged RIP2K (unknown origin) expressed in baculovirus expression system preincubated for 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G162SQPubMed
LigandPNGBDBM25198(3-[(6-methanesulfonylquinolin-4-yl)amino]-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of RIP2K in MDP-stimulated HEK-293 cells over-expressing NOD2 assessed as IL8 secretionMore data for this Ligand-Target Pair
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