Compile Data Set for Download or QSAR
Found 35 with Last Name = 'knapp-reed' and Initial = 'ba'
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245983((2R,3S,4S)-2-Ethyl-3-methyl-N-[3,5-(chloro)phenyl]...)copy SMILEScopy InChI
Affinity DataKi:  70nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246518(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245937((2R,3S,4S)-N-(3-bromophenyl)-2-ethyl-3-methyl-4-(p...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245772((4-bromophenyl)((2R,3S,4S)-2-ethyl-3-methyl-4-(phe...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245982((2R,3S,4S)-N-(3,5-dimethoxyphenyl)-2-ethyl-3-methy...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245835((2R,3S,4S)-N-(3-chlorophenyl)-2-ethyl-3-methyl-4-(...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245934((2R,3S,4S)-N-(4-chlorophenyl)-2-ethyl-3-methyl-4-(...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246516(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246517((4-chlorophenyl)((2R,3S,4S)-2-ethyl-3-methyl-4-(ph...)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245981((2R,3S,4S)-2-ethyl-3-methyl-N-phenyl-4-(phenylamin...)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246468(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245935((2R,3S,4S)-2-ethyl-N-(3-methoxyphenyl)-3-methyl-4-...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245984(CHEMBL516508 | cis-(2(R)-ethyl-4-(phenylamino)-3,4...)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Displacement of [33P]2-Mes-ADP from human recombinant P2Y1 receptor expressed in human U20S cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245983((2R,3S,4S)-2-Ethyl-3-methyl-N-[3,5-(chloro)phenyl]...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246516(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245982((2R,3S,4S)-N-(3,5-dimethoxyphenyl)-2-ethyl-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245772((4-bromophenyl)((2R,3S,4S)-2-ethyl-3-methyl-4-(phe...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246518(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245937((2R,3S,4S)-N-(3-bromophenyl)-2-ethyl-3-methyl-4-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245835((2R,3S,4S)-N-(3-chlorophenyl)-2-ethyl-3-methyl-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246517((4-chlorophenyl)((2R,3S,4S)-2-ethyl-3-methyl-4-(ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245981((2R,3S,4S)-2-ethyl-3-methyl-N-phenyl-4-(phenylamin...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245935((2R,3S,4S)-2-ethyl-N-(3-methoxyphenyl)-3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246468(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245934((2R,3S,4S)-N-(4-chlorophenyl)-2-ethyl-3-methyl-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245984(CHEMBL516508 | cis-(2(R)-ethyl-4-(phenylamino)-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245936((2R,3S,4S)-2-ethyl-N-(4-methoxyphenyl)-3-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246030((4-methoxyphenyl)((3R,4S)-3-methyl-4-(phenylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246031((S)-(4-methoxyphenyl)(4-(phenylamino)-3,4-dihydroq...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245774(((2R,3R,4S)-2-ethyl-3-methyl-4-(methyl(phenyl)amin...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245773(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246515(((2R,3S,4S)-2-ethyl-3-methyl-4-(phenylamino)-3,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50245775((2R,3S,4S)-N-(2-chlorophenyl)-2-ethyl-3-methyl-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246032((2S,3R,4R)-N-(3,5-dichlorophenyl)-2-ethyl-3-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50246029(CHEMBL473095 | trans-((2(R)-ethyl-4-(phenylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at human P2Y1 receptor in HEK293 cells assessed as intracellular calcium level by FLIPRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1X42PubMed