Compile Data Set for Download or QSAR
Found 42 with Last Name = 'willis' and Initial = 'ba'
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM400979(US9999624, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 0.275nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 0.309nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 2(Homo sapiens (Human))TBA
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)copy SMILEScopy InChI
Affinity DataIC50: 0.388nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)copy SMILEScopy InChI
Affinity DataIC50: 0.481nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 2(Homo sapiens (Human))TBA
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 0.555nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)copy SMILEScopy InChI
Affinity DataIC50: 0.603nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM400979(US9999624, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 0.615nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 2(Homo sapiens (Human))TBA
LigandPNGBDBM400979(US9999624, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 0.871nMAssay Description:Inhibition of recombinant human BACE2 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50012647(CHEMBL2396989)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540172(CHEMBL4637426)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50012647(CHEMBL2396989)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540171(CHEMBL4643727)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581133(CHEMBL5093835)copy SMILES
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581135(CHEMBL3701715)copy SMILES
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581132(CHEMBL5088790)copy SMILES
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50012632(CHEMBL2333941)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581136(CHEMBL3701713)copy SMILES
Affinity DataIC50: 172nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50012632(CHEMBL2333941)copy SMILEScopy InChI
Affinity DataIC50: 239nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50581132(CHEMBL5088790)copy SMILES
Affinity DataIC50: 275nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50581133(CHEMBL5093835)copy SMILES
Affinity DataIC50: 324nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50581134(CHEMBL5091705)copy SMILES
Affinity DataIC50: 470nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50540168(CHEMBL4644249)copy SMILEScopy InChI
Affinity DataIC50: 991nMAssay Description:Inhibition of recombinant human BACE1 using (MCA)-S-E-V-N-L-D-A-E-F-R-K(dinitrophenol)-R-R-R-R-NH2 as substrate incubated for 8 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50581135(CHEMBL3701715)copy SMILES
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50581134(CHEMBL5091705)copy SMILES
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetBeta-secretase 1(Mus musculus (Mouse))TBA
LigandPNGBDBM50581136(CHEMBL3701713)copy SMILES
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of BACE1 in mouse primary cortical neuron assessed as reduction in Amyloid-beta level incubated for 24 hrs by sandwich ELISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
LigandPNGBDBM400979(US9999624, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50581135(CHEMBL3701715)copy SMILES
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50012632(CHEMBL2333941)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50581133(CHEMBL5093835)copy SMILES
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50581136(CHEMBL3701713)copy SMILES
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50581132(CHEMBL5088790)copy SMILES
Affinity DataIC50: 4.09E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM400979(US9999624, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50581134(CHEMBL5091705)copy SMILES
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50540171(CHEMBL4643727)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+5nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50540172(CHEMBL4637426)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50540168(CHEMBL4644249)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed
TargetCathepsin D(Homo sapiens (Human))TBA
LigandPNGBDBM50012647(CHEMBL2396989)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human Cathepsin D by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0KBWPubMed