Compile Data Set for Download or QSAR
Found 32 with Last Name = 'lee' and Initial = 'bc'
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50483880(CHEMBL1774642)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50483881(CHEMBL1774643)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)copy SMILEScopy InChI
Affinity DataKi:  0.530nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090213(6-Bromo-2-piperazin-1-yl-quinoline | CHEMBL39164)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM25870(1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]PIB from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090216(6-Chloro-2-piperazin-1-yl-quinoline | CHEMBL290537)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090215(2-[1,4]Diazepan-1-yl-6-nitro-quinoline | CHEMBL431...)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50483880(CHEMBL1774642)copy SMILEScopy InChI
Affinity DataKi:  5.5nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50483881(CHEMBL1774643)copy SMILEScopy InChI
Affinity DataKi:  5.90nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090210(6-Iodo-2-piperazin-1-yl-quinoline | CHEMBL38466)copy SMILEScopy InChI
Affinity DataKi:  6.60nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090217(CHEMBL39265 | N,N'-Dimethyl-N-(6-nitro-quinolin-2-...)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090214(3-Bromo-6-nitro-2-piperazin-1-yl-quinoline | CHEMB...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090211(2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline | CH...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Seoul National University Bundang Hospital

Curated by ChEMBL
LigandPNGBDBM50483882(CHEMBL284575)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Displacement of [125I]TZDM from amyloid beta (1 to 42) aggregates in Alzheimer's disease-human brain homogenate after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21839CGPubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)copy SMILEScopy InChI
Affinity DataKi:  63nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090212(CHEMBL38754 | N*1*-(6-Nitro-quinolin-2-yl)-ethane-...)copy SMILEScopy InChI
Affinity DataKi:  164nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50090218(6,8-Dinitro-2-piperazin-1-yl-quinoline | CHEMBL377...)copy SMILEScopy InChI
Affinity DataKi:  313nMAssay Description:Inhibition of [3H]citalopram binding to Serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P10J2PubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335908(CHEMBL1668774 | tuberatolide B)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335909(2'-epi-Tuberatolide B | CHEMBL1668775)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335907(CHEMBL1668773 | tuberatolide A)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335910(CHEMBL1668776 | yezoquinolide)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335911((R)-sargachromenol | CHEMBL1668777)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50335912((S)-sargachromenol | CHEMBL1668778)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Antagonist activity at human FXR expressed in CV-1 cells assessed as inhibition of CDCA-induced transactivation after 24 hrs by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2QZVPubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+5nMAssay Description:Inhibition of mushroom tyrosinase after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FVBPubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50213414(CHEMBL240528 | afzelin | kaempferol 3-O-alpha-L-rh...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of mushroom tyrosinase after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FVBPubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50331857(CHEMBL1289337 | alpha-rhamnoisorobin)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of mushroom tyrosinase after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FVBPubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50331856(CHEMBL251766 | Karempferitrin | kaempferitrin | ka...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of mushroom tyrosinase after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5FVBPubMed