Compile Data Set for Download or QSAR
Found 560 with Last Name = 'mckibben' and Initial = 'bp'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394245(US9975882, Example 36)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394268(US9975882, Example 59)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394250(US9975882, Example 41)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394237(US9975882, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394253(US9975882, Example 44)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394231(US9975882, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394260(US9975882, Example 51)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394262(US9975882, Example 53)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394211(US9975882, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394215(US9975882, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394242(US9975882, Example 33)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394214(US9975882, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394212(US9975882, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394267(US9975882, Example 58)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394223(US9975882, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394221(US9975882, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394269(US9975882, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394219(US9975882, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394256(US9975882, Example 47)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394263(US9975882, Example 54)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394241(US9975882, Example 32)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394239(US9975882, Example 30)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394265(US9975882, Example 56)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394218(US9975882, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394227(US9975882, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303361(US10138222, Example 76)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394220(US9975882, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394231(US9975882, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394243(US9975882, Example 34)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394264(US9975882, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394233(US9975882, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394238(US9975882, Example 29)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394246(US9975882, Example 37)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394240(US9975882, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394260(US9975882, Example 51)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394211(US9975882, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM1773(US10280174, Comparative Compound 1 | US8476284, 4 ...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394268(US9975882, Example 59)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303364(BDBM303369 | US10138222, Example 79)copy SMILEScopy InChI
Affinity DataIC50: 0.810nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394271(5-amino-1-(7-but-2-ynoyl-7-azaspiro[3.4]octan-2-yl...)copy SMILES
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303360(US10138222, Example 75)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394228(US9975882, Example 19)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394266(US9975882, Example 57)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394244(US9975882, Example 35)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394217(US9975882, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394248(US9975882, Example 39)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303438(US10138222, Example 166)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303440(US10138222, Example 168)copy SMILEScopy InChI
Affinity DataIC50: 0.950nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University of Kalmar

LigandPNGBDBM394245(US9975882, Example 36)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Lanthscreen Eu Kinase Binding assay for BMX is performed as described above for BTK except that 1 nM human recombinant full length TEC (His-tagged) k...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BP0531US Patent
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International GmbH

US Patent
LigandPNGBDBM303380(US10138222, Example 105)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0QS2US Patent
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